Literature DB >> 12600315

Membrane fusion.

Reinhard Jahn1, Thorsten Lang, Thomas C Südhof.   

Abstract

Membrane fusion, one of the most fundamental processes in life, occurs when two separate lipid membranes merge into a single continuous bilayer. Fusion reactions share common features, but are catalyzed by diverse proteins. These proteins mediate the initial recognition of the membranes that are destined for fusion and pull the membranes close together to destabilize the lipid/water interface and to initiate mixing of the lipids. A single fusion protein may do everything or assemblies of protein complexes may be required for intracellular fusion reactions to guarantee rigorous regulation in space and time. Cellular fusion machines are adapted to fit the needs of different reactions but operate by similar principles in order to achieve merging of the bilayers.

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Year:  2003        PMID: 12600315     DOI: 10.1016/s0092-8674(03)00112-0

Source DB:  PubMed          Journal:  Cell        ISSN: 0092-8674            Impact factor:   41.582


  466 in total

1.  Direct simulation of protein-mediated vesicle fusion: lung surfactant protein B.

Authors:  Svetlana Baoukina; D Peter Tieleman
Journal:  Biophys J       Date:  2010-10-06       Impact factor: 4.033

Review 2.  The diversity and commonalities of gastroenteropancreatic neuroendocrine tumors.

Authors:  Simon Schimmack; Bernhard Svejda; Benjamin Lawrence; Mark Kidd; Irvin M Modlin
Journal:  Langenbecks Arch Surg       Date:  2011-01-28       Impact factor: 3.445

3.  Single-molecule fluorescence resonance energy transfer reveals a dynamic equilibrium between closed and open conformations of syntaxin 1.

Authors:  M Margittai; J Widengren; E Schweinberger; G F Schröder; S Felekyan; E Haustein; M König; D Fasshauer; H Grubmüller; R Jahn; C A M Seidel
Journal:  Proc Natl Acad Sci U S A       Date:  2003-12-10       Impact factor: 11.205

4.  Protein kinases talk to lipid phosphatases at the synapse.

Authors:  Bogachan Sahin; James A Bibb
Journal:  Proc Natl Acad Sci U S A       Date:  2004-01-26       Impact factor: 11.205

5.  A capsid protein of nonenveloped Bluetongue virus exhibits membrane fusion activity.

Authors:  Mario Forzan; Christoph Wirblich; Polly Roy
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-04       Impact factor: 11.205

6.  Constitutive versus regulated SNARE assembly: a structural basis.

Authors:  Yong Chen; Yibin Xu; Fan Zhang; Yeon-Kyun Shin
Journal:  EMBO J       Date:  2004-02-05       Impact factor: 11.598

7.  The SNARE Ykt6 mediates protein palmitoylation during an early stage of homotypic vacuole fusion.

Authors:  Lars E P Dietrich; Rolf Gurezka; Michael Veit; Christian Ungermann
Journal:  EMBO J       Date:  2003-12-11       Impact factor: 11.598

8.  Identification of SNARE complex modulators that inhibit exocytosis from an alpha-helix-constrained combinatorial library.

Authors:  Clara Blanes-Mira; Maria T Pastor; Elvira Valera; Gregorio Fernández-Ballester; Jaime M Merino; Luis M Gutierrez; Enrique Perez-Payá; Antonio Ferrer-Montiel
Journal:  Biochem J       Date:  2003-10-01       Impact factor: 3.857

9.  Synaptobrevin2 is the v-SNARE required for cytotoxic T-lymphocyte lytic granule fusion.

Authors:  Ulf Matti; Varsha Pattu; Mahantappa Halimani; Claudia Schirra; Elmar Krause; Yuanyuan Liu; Lisa Weins; Hsin Fang Chang; Raul Guzman; Jenny Olausson; Marc Freichel; Frank Schmitz; Mathias Pasche; Ute Becherer; Dieter Bruns; Jens Rettig
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

10.  Resolving vesicle fusion from lysis to monitor calcium-triggered lysosomal exocytosis in astrocytes.

Authors:  Jyoti K Jaiswal; Marina Fix; Takahiro Takano; Maiken Nedergaard; Sanford M Simon
Journal:  Proc Natl Acad Sci U S A       Date:  2007-08-21       Impact factor: 11.205

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