OBJECTIVE: To observe the effects of rice flavoids (RF) on learning and memory functions. METHODS: The step down test and the step through test in mice were used. RESULTS: RF could significantly improve the learning and memory ability in many dementia models, such as the impairment of acquisition of memory mice induced by M-anticholinergic agents like anisodine, the impairment of consolidation of memory in mice induced by protein biosynthesis inhibitors like actidione, the impairment of retrieval of memory in mice induced by central neuron system(CNS) depressants like ethanol, mice after cerebral ischemia-reperfusion. CONCLUSION: It is suggested that RF can markedly enhance the learning and memory ability, and that is significant to prevent and cure the senile dementia.
OBJECTIVE: To observe the effects of riceflavoids (RF) on learning and memory functions. METHODS: The step down test and the step through test in mice were used. RESULTS: RF could significantly improve the learning and memory ability in many dementia models, such as the impairment of acquisition of memory mice induced by M-anticholinergic agents like anisodine, the impairment of consolidation of memory in mice induced by protein biosynthesis inhibitors like actidione, the impairment of retrieval of memory in mice induced by central neuron system(CNS) depressants like ethanol, mice after cerebral ischemia-reperfusion. CONCLUSION: It is suggested that RF can markedly enhance the learning and memory ability, and that is significant to prevent and cure the senile dementia.