BACKGROUND: The aim of this study was to evaluate the usefulness of thallium-201 (Tl-201) single-photon emission CT (SPECT) to detect recurrent nasopharyngeal carcinomas (NPC) when MRI findings are indeterminate. METHODS: After radiotherapy, 26 NPC patients with indeterminate MRI findings were included in this study. MRI, Tl-201, and biopsy were performed at least 4 months after radiotherapy and within 1 week. The final results were based on histopathologic findings and clinical follow-up after at least 6 months. RESULTS: For detecting recurrent NPC in indeterminate MRI findings, the sensitivity, specificity, and accuracy of Tl-201 SPECT were 92.3%, 92.3%, and 92.3%, respectively. CONCLUSIONS: On the basis of this result, Tl-201 SPECT seems to be effective in detecting recurrent NPC when MRI findings are indeterminate. Copyright 2003 Wiley Periodicals, Inc. Head Neck 25: 227-231, 2003
BACKGROUND: The aim of this study was to evaluate the usefulness of thallium-201 (Tl-201) single-photon emission CT (SPECT) to detect recurrent nasopharyngeal carcinomas (NPC) when MRI findings are indeterminate. METHODS: After radiotherapy, 26 NPC patients with indeterminate MRI findings were included in this study. MRI, Tl-201, and biopsy were performed at least 4 months after radiotherapy and within 1 week. The final results were based on histopathologic findings and clinical follow-up after at least 6 months. RESULTS: For detecting recurrent NPC in indeterminate MRI findings, the sensitivity, specificity, and accuracy of Tl-201 SPECT were 92.3%, 92.3%, and 92.3%, respectively. CONCLUSIONS: On the basis of this result, Tl-201 SPECT seems to be effective in detecting recurrent NPC when MRI findings are indeterminate. Copyright 2003 Wiley Periodicals, Inc. Head Neck 25: 227-231, 2003
Authors: Andrew Thamboo; Kim H Tran; Annette X Ye; Issraa Shoucair; Basel Jabarin; Eitan Prisman; Cathie Garnis Journal: World J Otorhinolaryngol Head Neck Surg Date: 2022-04-21