Literature DB >> 1259890

Placental transfer of 14C-dimethyltubocurarine during Caesarean section.

I Kivalo, S Saarikoski.   

Abstract

Placental transfer of 14C-dimethyltubocurarine (14C-dmtc) was studied during Caesarean section. Liquid scintillation counting was used for determination of 14C activity from the maternal and foetal blood samples. Paper chromatography was used to confirm the stability of 14C-dmtc. In all cases 14C-dmtc was able to cross the placenta. Detectable amounts of 14C-dmtc were found in umbilical blood 2 min after injection into the mother. Six and 10 min after injection, the 14C concentration in the umbilical blood was 12% of the corresponding maternal value.

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Year:  1976        PMID： 1259890     DOI： 10.1093/bja/48.3.239

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN： 0007-0912            Impact factor:   9.166


  6 in total

1.  Residual curarization in the neonate after caesarean section.

Authors:  C Perreault; J Guay; P Gaudreault; L Cyrenne; F Varin
Journal:  Can J Anaesth       Date:  1991-07       Impact factor: 5.063

2.  Clinical pharmacokinetics of muscle relaxants.

Authors:  L B Wingard; D R Cook
Journal:  Clin Pharmacokinet       Date:  1977 Sep-Oct       Impact factor: 6.447

Review 3.  Clinical pharmacokinetics of the non-depolarising muscle relaxants.

Authors:  M I Ramzan; A A Somogyi; J S Walker; C A Shanks; E J Triggs
Journal:  Clin Pharmacokinet       Date:  1981 Jan-Feb       Impact factor: 6.447

Review 4.  Drug kinetics in childbirth.

Authors:  R L Nation
Journal:  Clin Pharmacokinet       Date:  1980 Jul-Aug       Impact factor: 6.447

Review 5.  Placental transfer of drugs administered to the mother.

Authors:  G M Pacifici; R Nottoli
Journal:  Clin Pharmacokinet       Date:  1995-03       Impact factor: 6.447

Review 6.  Models for placental transfer studies of drugs.

Authors:  P Bourget; C Roulot; H Fernandez
Journal:  Clin Pharmacokinet       Date:  1995-02       Impact factor: 6.447
  6 in total

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