Literature DB >> 12597259

Coenzyme Q10 and cardiovascular disease: a review.

Barbara Sarter1.   

Abstract

This article provides a comprehensive review of 30 years of research on the use of coenzyme Q10 in prevention and treatment of cardiovascular disease. This endogenous antioxidant has potential for use in prevention and treatment of cardiovascular disease, particularly hypertension, hyperlipidemia, coronary artery disease, and heart failure. It appears that levels of coenzyme Q10 are decreased during therapy with HMG-CoA reductase inhibitors, gemfibrozil, Adriamycin, and certain beta blockers. Further clinical trials are warranted, but because of its low toxicity it may be appropriate to recommend coenzyme Q10 to select patients as an adjunct to conventional treatment.

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Year:  2002        PMID： 12597259     DOI： 10.1097/00005082-200207000-00003

Source DB:  PubMed          Journal:  J Cardiovasc Nurs        ISSN： 0889-4655            Impact factor:   2.083


  15 in total

Review 1.  Liposomes in diagnosis and treatment of cardiovascular disorders.

Authors:  Tatyana S Levchenko; William C Hartner; Vladimir P Torchilin
Journal:  Methodist Debakey Cardiovasc J       Date:  2012-01

2.  Coenzyme Q10 Supplementation Modulates NFκB and Nrf2 Pathways in Exercise Training.

Authors:  Ragip Pala; Cemal Orhan; Mehmet Tuzcu; Nurhan Sahin; Shakir Ali; Vedat Cinar; Mustafa Atalay; Kazim Sahin
Journal:  J Sports Sci Med       Date:  2016-02-23       Impact factor: 2.988

3.  Low circulating coenzyme Q10 during acute phase is associated with inflammation, malnutrition, and in-hospital mortality in patients admitted to the coronary care unit.

Authors:  Megumi Shimizu; Tetsuro Miyazaki; Atsutoshi Takagi; Yurina Sugita; Shoichiro Yatsu; Azusa Murata; Takao Kato; Shoko Suda; Shohei Ouchi; Tatsuro Aikawa; Masaru Hiki; Shuhei Takahashi; Makoto Hiki; Hidemori Hayashi; Takatoshi Kasai; Kazunori Shimada; Katsumi Miyauchi; Hiroyuki Daida
Journal:  Heart Vessels       Date:  2016-12-09       Impact factor: 2.037

4.  Effects of an ergosterol synthesis inhibitor on gene transcription of terpenoid biosynthesis in Blakeslea trispora.

Authors:  Qiong Tang; Ye Li; Qi-Peng Yuan
Journal:  Curr Microbiol       Date:  2008-09-04       Impact factor: 2.188

5.  Protective effect of coenzyme Q10-loaded liposomes on the myocardium in rabbits with an acute experimental myocardial infarction.

Authors:  Daya D Verma; William C Hartner; Vineet Thakkar; Tatyana S Levchenko; Vladimir P Torchilin
Journal:  Pharm Res       Date:  2007-07-27       Impact factor: 4.200

6.  Cardioprotective effect of ascorbic acid on doxorubicin-induced myocardial toxicity in rats.

Authors:  A H M Viswanatha Swamy; U Wangikar; B C Koti; A H M Thippeswamy; P M Ronad; D V Manjula
Journal:  Indian J Pharmacol       Date:  2011-09       Impact factor: 1.200

7.  The relationship between coenzyme Q10, oxidative stress, and antioxidant enzymes activities and coronary artery disease.

Authors:  Bor-Jen Lee; Yi-Chin Lin; Yi-Chia Huang; Ya-Wen Ko; Simon Hsia; Ping-Ting Lin
Journal:  ScientificWorldJournal       Date:  2012-05-03

Review 8.  Nanoscale Technologies for Prevention and Treatment of Heart Failure: Challenges and Opportunities.

Authors:  Mohammad Javad Hajipour; Mehdi Mehrani; Seyed Hesameddin Abbasi; Ahmad Amin; Seyed Ebrahim Kassaian; Jessica C Garbern; Giulio Caracciolo; Steven Zanganeh; Mitra Chitsazan; Haniyeh Aghaverdi; Seyed Mehdi Kamali Shahri; Aliakbar Ashkarran; Mohammad Raoufi; Holly Bauser-Heaton; Jianyi Zhang; Jochen D Muehlschlegel; Anna Moore; Richard T Lee; Joseph C Wu; Vahid Serpooshan; Morteza Mahmoudi
Journal:  Chem Rev       Date:  2019-09-06       Impact factor: 60.622

9.  New susceptible variant of COQ2 gene in Japanese patients with sporadic multiple system atrophy.

Authors:  Zhuoran Sun; Yasuyuki Ohta; Toru Yamashita; Kota Sato; Mami Takemoto; Nozomi Hishikawa; Koji Abe
Journal:  Neurol Genet       Date:  2016-03-03

10.  Effects of coenzyme Q10 supplementation on C-reactive protein and homocysteine as the inflammatory markers in hemodialysis patients; a randomized clinical trial.

Authors:  Narges-Sadat Zahed; Maryam Ghassami; Hajar Nikbakht
Journal:  J Nephropathol       Date:  2015-11-07
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