Literature DB >> 12597021

Immunopotentiating activity of abrin, a lectin from Abrus precatorius Linn.

V Ramnath1, Girija Kuttan, Ramadasan Kuttan.   

Abstract

A non-toxic dose of abrin, (1.25 microg/kg body wt) consecutively for five days in normal mice stimulated specific humoral responses. A noticeable increase was observed in total leucocyte count, lymphocytosis, weights of spleen and thymus, circulating antibody titre, antibody forming cells, bone marrow cellularity and alpha-esterase positive bone marrow cells. The results suggest that abrin can potentiate the humoral immune response of the host.

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Year:  2002        PMID: 12597021

Source DB:  PubMed          Journal:  Indian J Exp Biol        ISSN: 0019-5189            Impact factor:   0.818


  6 in total

1.  Cytotoxic and pro-apoptotic effects of Abrus precatorius L. on human metastatic breast cancer cell line, MDA-MB-231.

Authors:  Mohammed Shafi Sofi; M K Sateesh; Mohsin Bashir; G Harish; T R Lakshmeesha; S Vedashree; A B Vedamurthy
Journal:  Cytotechnology       Date:  2012-10-19       Impact factor: 2.058

2.  Involvement of prohibitin upregulation in abrin-triggered apoptosis.

Authors:  Yu-Huei Liu; Konan Peck; Jung-Yaw Lin
Journal:  Evid Based Complement Alternat Med       Date:  2011-09-25       Impact factor: 2.629

Review 3.  Geriatric management in medieval Persian medicine.

Authors:  Morteza Emami; Omid Sadeghpour; Mohammad M Zarshenas
Journal:  J Midlife Health       Date:  2013-10

4.  Antiasthmatic related properties of Abrus precatorius leaves on various models.

Authors:  Dnyaneshwar J Taur; Rajendra N Patil; Ravindra Y Patil
Journal:  J Tradit Complement Med       Date:  2017-01-12

5.  A Case of Poisoning with Abrus precatarius Complicated with Bilateral Basal Ganglia Haemorrhage.

Authors:  Arun Rajaratnam; Kishan Dissanayake; Kiertie Kularatne; Sunil Bowattage
Journal:  Case Rep Neurol Med       Date:  2022-08-25

6.  Regulation of Caspase-3 and Bcl-2 Expression in Dalton's Lymphoma Ascites Cells by Abrin.

Authors:  V Ramnath; P S Rekha; G Kuttan; R Kuttan
Journal:  Evid Based Complement Alternat Med       Date:  2007-11-01       Impact factor: 2.629

  6 in total

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