OBJECTIVE: To investigate the distribution of mophine in organs in cases with morphine poisioning to select ideal organs for immunohistochemical derection. METHODS: Localization and half quantitation of morphine in the brain, the kidney, the heart, and the liver were studied in 8 cases with morphine poisoning by immunohistochemical SP method. RESULTS: Morphine was mainly detected in the cytoplasm of certain parenchymal cells of the organs. The distribution varied greatly with different cases and organs. In the brain and kidney, morphine-positive cells could be easily found. CONCLUSION: The kidney and brain may be the ideal organs for sampling in suspected morphine poisoning cases with.
OBJECTIVE: To investigate the distribution of mophine in organs in cases with morphine poisioning to select ideal organs for immunohistochemical derection. METHODS: Localization and half quantitation of morphine in the brain, the kidney, the heart, and the liver were studied in 8 cases with morphinepoisoning by immunohistochemical SP method. RESULTS:Morphine was mainly detected in the cytoplasm of certain parenchymal cells of the organs. The distribution varied greatly with different cases and organs. In the brain and kidney, morphine-positive cells could be easily found. CONCLUSION: The kidney and brain may be the ideal organs for sampling in suspected morphinepoisoning cases with.