Literature DB >> 12595482

Expression of variant surface antigens by Plasmodium falciparum parasites in the peripheral blood of clinically immune pregnant women indicates ongoing placental infection.

Michael F Ofori1, Trine Staalsoe, Victoria Bam, Maja Lundquist, Kim P David, Edmund N L Browne, Bartholomew D Akanmori, Lars Hviid.   

Abstract

Placenta-sequestered Plasmodium falciparum parasites that cause pregnancy-associated malaria (PAM) in otherwise clinically immune women express distinct variant surface antigens (VSA(PAM)) not expressed by parasites in nonpregnant individuals. We report here that parasites from the peripheral blood of clinically immune pregnant women also express VSA(PAM), making them a convenient source of VSA(PAM) expressors for PAM vaccine research.

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Year:  2003        PMID： 12595482      PMCID： PMC148875          DOI： 10.1128/IAI.71.3.1584-1586.2003

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  20 in total

1.  Submicroscopic Plasmodium falciparum infections in pregnancy in Ghana.

Authors:  F P Mockenhaupt; B Rong; H Till; T A Eggelte; S Beck; C Gyasi-Sarpong; W N Thompson; U Bienzle
Journal:  Trop Med Int Health       Date:  2000-03       Impact factor: 2.622

2.  Malaria, anaemia and pregnancy.

Authors:  H M Gilles; J B Lawson; M Sibelas; A Voller; N Allan
Journal:  Ann Trop Med Parasitol       Date:  1969-06

3.  An analysis of malaria in pregnancy in Africa.

Authors:  B J Brabin
Journal:  Bull World Health Organ       Date:  1983       Impact factor: 9.408

4.  Plasma antibodies from malaria-exposed pregnant women recognize variant surface antigens on Plasmodium falciparum-infected erythrocytes in a parity-dependent manner and block parasite adhesion to chondroitin sulfate A.

Authors:  C H Ricke; T Staalsoe; K Koram; B D Akanmori; E M Riley; T G Theander; L Hviid
Journal:  J Immunol       Date:  2000-09-15       Impact factor: 5.422

5.  Acquisition and decay of antibodies to pregnancy-associated variant antigens on the surface of Plasmodium falciparum-infected erythrocytes that protect against placental parasitemia.

Authors:  T Staalsoe; R Megnekou; N Fievét; C H Ricke; H D Zornig; R Leke; D W Taylor; P Deloron; L Hviid
Journal:  J Infect Dis       Date:  2001-08-09       Impact factor: 5.226

Review 6.  Malaria in pregnancy as an indirect cause of infant mortality in sub-Saharan Africa.

Authors:  H L Guyatt; R W Snow
Journal:  Trans R Soc Trop Med Hyg       Date:  2001 Nov-Dec       Impact factor: 2.184

Review 7.  The epidemiology and burden of Plasmodium falciparum-related anemia among pregnant women in sub-Saharan Africa.

Authors:  H L Guyatt; R W Snow
Journal:  Am J Trop Med Hyg       Date:  2001 Jan-Feb       Impact factor: 2.345

8.  Malaria-induced acquisition of antibodies to Plasmodium falciparum variant surface antigens.

Authors:  Michael F Ofori; Daniel Dodoo; Trine Staalsoe; Jørgen A L Kurtzhals; Kwadwo Koram; Thor G Theander; Bartholomew D Akanmori; Lars Hviid
Journal:  Infect Immun       Date:  2002-06       Impact factor: 3.441

9.  Cytoadhesion of Plasmodium falciparum ring-stage-infected erythrocytes.

Authors:  B Pouvelle; P A Buffet; C Lépolard; A Scherf; J Gysin
Journal:  Nat Med       Date:  2000-11       Impact factor: 53.440

10.  Gravidity-dependent production of antibodies that inhibit binding of Plasmodium falciparum-infected erythrocytes to placental chondroitin sulfate proteoglycan during pregnancy.

Authors:  I O'Neil-Dunne; R N Achur; S T Agbor-Enoh; M Valiyaveettil; R S Naik; C F Ockenhouse; A Zhou; R Megnekou; R Leke; D W Taylor; D C Gowda
Journal:  Infect Immun       Date:  2001-12       Impact factor: 3.441
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  14 in total

1.  Phenotypes of Plasmodium falciparum from the peripheral blood of pregnant women.

Authors:  James G Beeson; Stephen J Rogerson
Journal:  Infect Immun       Date:  2004-03       Impact factor: 3.441

2.  Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants.

Authors:  Lea Barfod; Tina Dobrilovic; Pamela Magistrado; Pongsak Khunrae; Firmine Viwami; Jonas Bruun; Madeleine Dahlbäck; Nadia L Bernasconi; Michal Fried; Davis John; Patrick E Duffy; Ali Salanti; Antonio Lanzavecchia; Chwee Teck Lim; Nicaise Tuikue Ndam; Matthew K Higgins; Lars Hviid
Journal:  J Immunol       Date:  2010-11-15       Impact factor: 5.422

3.  Effects of pregnancy and intensity of Plasmodium falciparum transmission on immunoglobulin G subclass responses to variant surface antigens.

Authors:  Rosette Megnekou; Trine Staalsoe; Diane W Taylor; Rose Leke; Lars Hviid
Journal:  Infect Immun       Date:  2005-07       Impact factor: 3.441

4.  Plasmodium falciparum parasites expressing pregnancy-specific variant surface antigens adhere strongly to the choriocarcinoma cell line BeWo.

Authors:  Rikke N Haase; Rosette Megnekou; Maja Lundquist; Michael F Ofori; Lars Hviid; Trine Staalsoe
Journal:  Infect Immun       Date:  2006-05       Impact factor: 3.441

5.  Kinetics of B cell responses to Plasmodium falciparum erythrocyte membrane protein 1 in Ghanaian women naturally exposed to malaria parasites.

Authors:  Paulina Ampomah; Liz Stevenson; Michael F Ofori; Lea Barfod; Lars Hviid
Journal:  J Immunol       Date:  2014-04-23       Impact factor: 5.422

6.  Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1.

Authors:  Lea Barfod; Michael B Dalgaard; Suzan T Pleman; Michael F Ofori; Richard J Pleass; Lars Hviid
Journal:  Proc Natl Acad Sci U S A       Date:  2011-07-11       Impact factor: 11.205

7.  Intermittent preventive treatment with sulfadoxine-pyrimethamine against malaria and anemia in pregnant women.

Authors:  Nana O Wilson; Fatou K Ceesay; Samuel A Obed; Andrew A Adjei; Richard K Gyasi; Patricia Rodney; Yassa Ndjakani; Winston A Anderson; Naomi W Lucchi; Jonathan K Stiles
Journal:  Am J Trop Med Hyg       Date:  2011-07       Impact factor: 2.345

8.  Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA.

Authors:  Lea Barfod; Nadia L Bernasconi; Madeleine Dahlbäck; David Jarrossay; Pernille Haste Andersen; Ali Salanti; Michael F Ofori; Louise Turner; Mafalda Resende; Morten A Nielsen; Thor G Theander; Federica Sallusto; Antonio Lanzavecchia; Lars Hviid
Journal:  Mol Microbiol       Date:  2006-12-14       Impact factor: 3.501

9.  Pregnancy-associated malaria in a rural community of ghana.

Authors:  Mf Ofori; E Ansah; I Agyepong; D Ofori-Adjei; L Hviid; Bd Akanmori
Journal:  Ghana Med J       Date:  2009-03

10.  Six genes are preferentially transcribed by the circulating and sequestered forms of Plasmodium falciparum parasites that infect pregnant women.

Authors:  Susan E Francis; Vladislav A Malkov; Andrew V Oleinikov; Eddie Rossnagle; Jason P Wendler; Theonest K Mutabingwa; Michal Fried; Patrick E Duffy
Journal:  Infect Immun       Date:  2007-08-13       Impact factor: 3.441
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