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Literature DB >> 12589342

Exhaled nitric oxide in asthma: from bench to bedside.

Abstract

With more than 600 publications, exhaled nitric oxide (NO) has been extensively investigated as a noninvasive marker of airway inflammation in a research setting. This clinical rostrum presents a synopsis of the latest research about this novel marker in asthma and suggests how it might move from bench to bedside. Specifically, we review the evidence citing the applicability of exhaled NO in diagnosing asthma, monitoring the response to therapy, evaluating current symptom control, and predicting exacerbations of asthma. These studies support a role for exhaled NO in the evaluation and treatment of asthma in the clinical arena.

Entities: Chemical Disease

Mesh：

Substances：

Year: 2003 PMID： 12589342 DOI： 10.1067/mai.2003.103

Source DB: PubMed Journal: J Allergy Clin Immunol ISSN： 0091-6749 Impact factor: 10.793

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Cited

14 in total

1. Changes in exhaled nitric oxide levels after bronchial allergen challenge.

Authors: María Pedrosa; Pilar Barranco; Valentín López-Carrasco; Santiago Quirce
Journal: Lung Date: 2012-01-07 Impact factor: 2.584

2. Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.

Authors: Wendy C Moore; Eugene R Bleecker; Douglas Curran-Everett; Serpil C Erzurum; Bill T Ameredes; Leonard Bacharier; William J Calhoun; Mario Castro; Kian Fan Chung; Melissa P Clark; Raed A Dweik; Anne M Fitzpatrick; Benjamin Gaston; Mark Hew; Iftikhar Hussain; Nizar N Jarjour; Elliot Israel; Bruce D Levy; James R Murphy; Stephen P Peters; W Gerald Teague; Deborah A Meyers; William W Busse; Sally E Wenzel
Journal: J Allergy Clin Immunol Date: 2007-02 Impact factor: 10.793

3. Genetic and epigenetic variations in inducible nitric oxide synthase promoter, particulate pollution, and exhaled nitric oxide levels in children.

Authors: Muhammad T Salam; Hyang-Min Byun; Fred Lurmann; Carrie V Breton; Xinhui Wang; Sandrah P Eckel; Frank D Gilliland
Journal: J Allergy Clin Immunol Date: 2011-11-04 Impact factor: 10.793

4. Pharmacokinetic and pharmacodynamic comparison of hydrofluoroalkane and chlorofluorocarbon formulations of budesonide.

Authors: Karine L Clearie; Peter A Williamson; Karen Meldrum; Michael Gillen; Lars-Goran Carlsson; Marie Carlholm; Jan Ekelund; Brian J Lipworth
Journal: Br J Clin Pharmacol Date: 2011-04 Impact factor: 4.335

Review 5. Exhaled nitric oxide: a test for diagnosis and control of asthma?

Authors: Rohit Katial; Lora Stewart
Journal: Curr Allergy Asthma Rep Date: 2007-11 Impact factor: 4.806

6. A novel subset of CD4(+) T(H)2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma.

Authors: Yui-Hsi Wang; Kui Shin Voo; Bo Liu; Chun-Yu Chen; Burcin Uygungil; William Spoede; Jonathan A Bernstein; David P Huston; Yong-Jun Liu
Journal: J Exp Med Date: 2010-10-04 Impact factor: 14.307

10. IL-8, IL-10, TGF-β, and GCSF levels were increased in severe persistent allergic asthma patients with the anti-IgE treatment.

Authors: Arzu D Yalcin; Atil Bisgin; Reginald M Gorczynski
Journal: Mediators Inflamm Date: 2012-12-19 Impact factor: 4.711