Richard D Griffiths1. 1. Intensive Care Research Group, Department of Medicien, University of Liverpool, Marseyside, UK. rdg@liverpool.ac.uk
Abstract
PURPOSE OF REVIEW: Infection and sepsis remain major challenges in the critically ill. How nutritional therapy can effect real clinical outcomes is not easily apparent from the clinical data. Despite reducing infectious incidence, many studies show little difference in meaningful clinical outcomes. RECENT FINDINGS: Confusion over the role that nutrition and nutrition practice in intensive care plays in preventing infection, and later how nutrition aids recovery from sepsis perhaps explains many of the misconceptions and difficulties with the evidence. SUMMARY: Encouraging new evidence will help our decision making and shows that outcome can be improved by performing relatively simple therapies well.
PURPOSE OF REVIEW: Infection and sepsis remain major challenges in the critically ill. How nutritional therapy can effect real clinical outcomes is not easily apparent from the clinical data. Despite reducing infectious incidence, many studies show little difference in meaningful clinical outcomes. RECENT FINDINGS: Confusion over the role that nutrition and nutrition practice in intensive care plays in preventing infection, and later how nutrition aids recovery from sepsis perhaps explains many of the misconceptions and difficulties with the evidence. SUMMARY: Encouraging new evidence will help our decision making and shows that outcome can be improved by performing relatively simple therapies well.
Authors: Peter Varga; Richard Griffiths; René Chiolero; Gérard Nitenberg; Xavier Leverve; Marek Pertkiewicz; Erich Roth; Jan Wernerman; Claude Pichard; Jean-Charles Preiser Journal: Intensive Care Med Date: 2003-11 Impact factor: 17.440
Authors: Ursula G Kyle; Philippe Jolliet; Laurence Genton; Christoph A Meier; Nouri Mensi; Jean-Daniel Graf; Jean-Claude Chevrolet; Claude Pichard Journal: Intensive Care Med Date: 2005-10-25 Impact factor: 17.440