Literature DB >> 12589080

Recently occurring adult tetanus in Korea: emphasis on immunization and awareness of tetanus.

Dong Hyeon Shin1, Ho Sung Yu, Jung Ho Park, Jong Hee Shin, Sei Jong Kim.   

Abstract

Since a nationwide childhood vaccination with tetanus toxoid, tetanus has become a rare disease in Korea. However, we recently experienced 17 cases of adult tetanus in a university hospital during a 21-month period. Seventy percent of the patients were female, and the mean age was 63 yr (range, 29-87). The majority (88.2%) of the patients did not get primary vaccinations for tetanus and decennial tetanus-diphtheria toxoid booster. Most patients (88.2%), who sustained acute injury, did not seek medical care for their wounds or did not receive the prophylaxis for tetanus. Tetanus was found most frequently among farmers. Tetanus was diagnosed initially only in 53% of patients. The case-fatality ratio was 23.5%. These cases show that recently occurring tetanus in Korea is a disease, affecting the elderly and the female who may have a lower immunity against tetanus, and the farmers who are likely to be exposed to Clostridium tetani. In addition, diagnosis of tetanus is often delayed in area where cases are seen infrequently. Therefore, improved education among patients and physicians, emphasis of anti-tetanus immunization and awareness of tetanus respectively, may be essential for the prevention of disease and the reduction of its mortality.

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Year:  2003        PMID: 12589080      PMCID: PMC3054981          DOI: 10.3346/jkms.2003.18.1.11

Source DB:  PubMed          Journal:  J Korean Med Sci        ISSN: 1011-8934            Impact factor:   2.153


  10 in total

1.  Incomplete immunity and missed vaccination opportunities in East African immigrants settling in Australia.

Authors:  Susan A Skull; Joanne Y Y Ngeow; Geoff Hogg; Beverley-Ann Biggs
Journal:  J Immigr Minor Health       Date:  2008-06

2.  Evaluation for tetanus antibodies in Korean-Americans living in the New York area: a pilot study.

Authors:  Kumar Alagappan; Richard Park; Sassan Naderi; Robert Silverman
Journal:  J Immigr Minor Health       Date:  2008-03-18

3.  Immunogenicity and safety of diphtheria-tetanus vaccine in adults.

Authors:  Jung-Hyun Choi; Eun Ju Choo; Aejung Huh; Su-Mi Choi; Joong Sik Eom; Jin Seo Lee; Sun Hee Park; Jin Han Kang
Journal:  J Korean Med Sci       Date:  2010-11-24       Impact factor: 2.153

4.  Influences on formation of tetanus antibody after simultaneous injection of tetanus immunoglobulin with tetanus vaccine.

Authors:  Jonghwan Shin; Jinjoo Kim; Kyoungjun Song
Journal:  J Korean Med Sci       Date:  2012-07-25       Impact factor: 2.153

Review 5.  Disease prevalence and mortality among agricultural workers in Korea.

Authors:  Won Jin Lee; Eun Shil Cha; Eun Kyeong Moon
Journal:  J Korean Med Sci       Date:  2010-12-15       Impact factor: 2.153

6.  Tetanus presenting primarily as periocular discomfort in a patient who underwent surgery for sleep apnea: A case report and brief literature review.

Authors:  Donghwi Park; Jung Soo Kim; Sung Jae Heo
Journal:  Medicine (Baltimore)       Date:  2019-06       Impact factor: 1.817

7.  Clinical outcomes and healthcare costs of inpatients with tetanus in Korea, 2011-2019.

Authors:  Sook-In Jung; Hyun-Ha Chang; Sohyun Bae; Minsik Go; Yoonjung Kim; Soyoon Hwang; Shin-Woo Kim; Ki Tae Kwon
Journal:  BMC Infect Dis       Date:  2021-03-09       Impact factor: 3.090

8.  Evaluation of immunogenicity and safety of the new tetanus-reduced diphtheria (Td) vaccines (GC1107) in healthy Korean adolescents: a phase II, double-blind, randomized, multicenter clinical trial.

Authors:  Jung-Woo Rhim; Kyung-Yil Lee; Sang-Yong Kim; Jong-Hyun Kim; Hyun-Hee Kim; Hwang Min Kim; Young-Youn Choi; Sang-Hyuk Ma; Dong-Ho Kim; Dong Ho Ahn; Jin-Han Kang
Journal:  J Korean Med Sci       Date:  2013-03-27       Impact factor: 2.153

9.  Clinician awareness of tetanus-diphtheria vaccination in trauma patients: a questionnaire study.

Authors:  Young-Hoon Yoon; Sung-Woo Moon; Sung-Hyuk Choi; Young-Duck Cho; Jung-Youn Kim; Young Ho Kwak
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2012-05-15       Impact factor: 2.953

10.  A Phase III Study to Evaluate the Immunogenicity and Safety of GC1107 (Adult Tetanus Diphtheria Vaccine) in Healthy Adults.

Authors:  Jacob Lee; Jung-Hyun Choi; Seong-Heon Wie; Sun Hee Park; Su-Mi Choi; Mi Suk Lee; Tae Hyong Kim; Hyo-Jin Lee; Jin Han Kang
Journal:  J Korean Med Sci       Date:  2019-01-16       Impact factor: 2.153

  10 in total

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