Literature DB >> 12587986

Chitin--the undisputed biomolecule of great potential.

Rudrapatnam N Tharanathan1, Farooqahmed S Kittur.   

Abstract

Of the truly abundant polysaccharides in Nature, only chitin has yet to find utilization in large quantity. Chitin is the second most abundant natural biopolymer derived from exoskeletons of crustaceans and also from cell walls of fungi and insects. Chitin is a linear beta 1,4-linked polymer of N-acetyl-D-glucosamine (GlcNAc), whereas chitosan, a copolymer of GlcNAc (approximately 20%) and glucosamine (GlcN, 80%) residues, is a product derived from de-N-acetylation of chitin in the presence of hot alkali. Chitosan is, in fact, a collective name representing a family of de-N-acetylated chitins deacetylated to different degrees. Both chitin/chitosan and their modified derivatives find extensive applications in medicine, agriculture, food, and non-food industries as well. They have emerged as a new class of physiological materials of highly sophisticated functions. Their application versatility is a great challenge to the scientific community and to industry. All these are the result of their versatile biological activity, excellent biocompatibility, and complete biodegradability in combination with low toxicity. Commercial availability of high-purity forms of chitin/chitosan and the continuous appearance of new types of chitin/chitosan derivatives with more and more useful and specific properties have led to an unlimited R&D efforts on this most versatile amino polysaccharide, chitin to find new applications, which are necessary to realize its full potential. Incidentally, this too has become an environmental priority. No doubt, chitin is surely an undisputed biomolecule of great potential.

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Year:  2003        PMID: 12587986     DOI: 10.1080/10408690390826455

Source DB:  PubMed          Journal:  Crit Rev Food Sci Nutr        ISSN: 1040-8398            Impact factor:   11.176


  85 in total

1.  Evolution, homology conservation, and identification of unique sequence signatures in GH19 family chitinases.

Authors:  N A Udaya Prakash; M Jayanthi; R Sabarinathan; P Kangueane; Lazar Mathew; K Sekar
Journal:  J Mol Evol       Date:  2010-05-18       Impact factor: 2.395

2.  Effect of chitosan edible films added with Thymus moroderi and Thymus piperella essential oil on shelf-life of cooked cured ham.

Authors:  Y Ruiz-Navajas; M Viuda-Martos; X Barber; E Sendra; J A Perez-Alvarez; J Fernández-López
Journal:  J Food Sci Technol       Date:  2015-01-21       Impact factor: 2.701

3.  Characterization of a cold-adapted and salt-tolerant exo-chitinase (ChiC) from Pseudoalteromonas sp. DL-6.

Authors:  Xiaohui Wang; Naiyu Chi; Fengwu Bai; Yuguang Du; Yong Zhao; Heng Yin
Journal:  Extremophiles       Date:  2016-01-20       Impact factor: 2.395

4.  Dual substrate specificity of an N-acetylglucosamine phosphotransferase system in Clostridium beijerinckii.

Authors:  Naief H Al Makishah; Wilfrid J Mitchell
Journal:  Appl Environ Microbiol       Date:  2013-08-30       Impact factor: 4.792

5.  Evolution of mammalian chitinase(-like) members of family 18 glycosyl hydrolases.

Authors:  Anton P Bussink; Dave Speijer; Johannes M F G Aerts; Rolf G Boot
Journal:  Genetics       Date:  2007-08-24       Impact factor: 4.562

6.  Salivary phosphate-binding chewing gum reduces hyperphosphatemia in dialysis patients.

Authors:  Vincenzo Savica; Lorenzo A Calò; Paolo Monardo; Paul A Davis; Antonio Granata; Domenico Santoro; Rodolfo Savica; Rosa Musolino; Maria Cristina Comelli; Guido Bellinghieri
Journal:  J Am Soc Nephrol       Date:  2008-11-19       Impact factor: 10.121

7.  Aromatic residues in the catalytic center of chitinase A from Serratia marcescens affect processivity, enzyme activity, and biomass converting efficiency.

Authors:  Henrik Zakariassen; Berit Bjugan Aam; Svein J Horn; Kjell M Vårum; Morten Sørlie; Vincent G H Eijsink
Journal:  J Biol Chem       Date:  2009-02-25       Impact factor: 5.157

8.  Chitin stimulates expression of acidic mammalian chitinase and eotaxin-3 by human sinonasal epithelial cells in vitro.

Authors:  Ashley Lalaker; Louis Nkrumah; Won-Kyung Lee; Murugappan Ramanathan; Andrew P Lane
Journal:  Am J Rhinol Allergy       Date:  2009 Jan-Feb       Impact factor: 2.467

9.  Insights into the mode of action of chitosan as an antibacterial compound.

Authors:  Dina Raafat; Kristine von Bargen; Albert Haas; Hans-Georg Sahl
Journal:  Appl Environ Microbiol       Date:  2008-05-02       Impact factor: 4.792

Review 10.  N-acetylglucosamine: production and applications.

Authors:  Jeen-Kuan Chen; Chia-Rui Shen; Chao-Lin Liu
Journal:  Mar Drugs       Date:  2010-09-15       Impact factor: 5.118

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