Literature DB >> 12587973

Inhibitors of apoptosis proteins in injury and disease.

George Lotocki1, Robert W Keane.   

Abstract

The inhibitor of apoptosis (IAP) gene family prevents cell death by binding to and inhibiting caspases. In addition to negatively regulating apoptosis, IAPs bind to signaling intermediates and receptors, and participate in diverse cellular functions. Here, we describe the physiological functions of IAPs and their participation in injury and disease processes.

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Year:  2002        PMID： 12587973     DOI： 10.1080/15216540215675

Source DB:  PubMed          Journal:  IUBMB Life        ISSN： 1521-6543            Impact factor:   3.885


  6 in total

Review 1.  Apoptotic cell death regulation in neurons.

Authors:  Emilie Hollville; Selena E Romero; Mohanish Deshmukh
Journal:  FEBS J       Date:  2019-07-12       Impact factor: 5.542

2.  Stable transfection of extrinsic Smac gene enhances apoptosis-inducing effects of chemotherapeutic drugs on gastric cancer cells.

Authors:  Li-Duan Zheng; Qiang-Song Tong; Liang Wang; Jun Liu; Wei Qian
Journal:  World J Gastroenterol       Date:  2005-01-07       Impact factor: 5.742

3.  Over-expression of X-linked inhibitor of apoptosis protein modulates multiple aspects of neuronal Ca2+ signaling.

Authors:  Jeff Grant; Kristen Parker; Craig S Moore; Paul G W Keddy; Michael Mayne; George S Robertson
Journal:  Neurochem Res       Date:  2013-02-10       Impact factor: 3.996

4.  Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats.

Authors:  Lana J Mawhinney; Juan Pablo de Rivero Vaccari; Gordon A Dale; Robert W Keane; Helen M Bramlett
Journal:  BMC Neurosci       Date:  2011-12-01       Impact factor: 3.288

5.  Sepantronium Bromide (YM155), A Small Molecule Survivin Inhibitor, Promotes Apoptosis by Induction of Oxidative Stress, Worsens the Behavioral Deficits and Develops an Early Model of Toxic Demyelination: In Vivo and In-Silico Study.

Authors:  Samaneh Reiszadeh-Jahromi; Mohammad-Reza Sepand; Samaneh Ramezani-Sefidar; Mohsen Shahlaei; Sajad Moradi; Meysam Yazdankhah; Nima Sanadgol
Journal:  Neurochem Res       Date:  2019-09-05       Impact factor: 4.414

6.  Role of XIAP gene overexpressed bone marrow mesenchymal stem cells in the treatment of cerebral injury in rats with cerebral palsy.

Authors:  Wenjing Deng; Chenghe Fan; Yanbo Fang; Yanan Zhao; Yamin Wei; Meng Li; Junfang Teng
Journal:  Cancer Cell Int       Date:  2019-10-23       Impact factor: 5.722
  6 in total

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