| Literature DB >> 12587696 |
B Parimala Devi1, R Boominathan, S C Mandal.
Abstract
A study was undertaken to evaluate the effect of a methanol extract of the entire plant Cleome viscosa L. (CVME) (Family; Capparidaceae) for its anti-diarrheal potential against some of the experimental models of diarrhea in rats. CVME showed significant inhibitory activity against castor-oil-induced diarrhea and PGE2 induced enteropooling in rats. The extract also showed a significant reduction in gastrointestinal motility in the charcoal meal test in rats. The results obtained establish the efficacy and substantiate the folklore claim as an anti-diarrheal agent.Entities:
Mesh：
Substances：
Year: 2002 PMID： 12587696 DOI： 10.1078/094471102321621368
Source DB: PubMed Journal: Phytomedicine ISSN： 0944-7113 Impact factor: 5.340