Literature DB >> 12587161

[Pharmacological comparison between virosecurinine and securinine].

H Pu1, J Zhao, B Pong, S Xu.   

Abstract

Pharmacological activities of virosecurinine (Vse) and securinine (Sec) were studied. The results showed that acute toxicity of Vse was 1/13.6 that of Sec, and Vse had no convulsive effects on rats or frogs, while Sec had. The results also showed that Vse and Sec could elevate blood pressure and excite respiration in cats.

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Year:  2001        PMID： 12587161

Source DB:  PubMed          Journal:  Zhong Yao Cai        ISSN： 1001-4454


  2 in total

1.  Securinine, a myeloid differentiation agent with therapeutic potential for AML.

Authors:  Kalpana Gupta; Amitabha Chakrabarti; Sonia Rana; Ritu Ramdeo; Bryan L Roth; Munna L Agarwal; William Tse; Mukesh K Agarwal; David N Wald
Journal:  PLoS One       Date:  2011-06-24       Impact factor: 3.240

2.  Securinine from Phyllanthus glaucus Induces Cell Cycle Arrest and Apoptosis in Human Cervical Cancer HeLa Cells.

Authors:  Justyna Stefanowicz-Hajduk; Barbara Sparzak-Stefanowska; Mirosława Krauze-Baranowska; J Renata Ochocka
Journal:  PLoS One       Date:  2016-10-28       Impact factor: 3.240
  2 in total

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