Literature DB >> 1258704

A nitrofurantoin-induced disorder simulating chronic active hepatitis. A case report.

B Fagrell, I Strandberg, B Wengle.   

Abstract

A 78-year-old woman with liver damage resembling chronic active hepatitis and occuring during long-term nitrofurantoin treatment is described. On admission to hospital she displayed jaundice, ascites and high serum levels of GOT, GPT, bilirubin and gamma-globulin as well as high titres of ANF and antibodies against smooth muscle cells. After withdrawal of nitrofurantoin the clinical and laboratory picture normalized without corticosteroid treatment, suggesting that the liver reaction was drug-induced.

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Year:  1976        PMID: 1258704     DOI: 10.1111/j.0954-6820.1976.tb06724.x

Source DB:  PubMed          Journal:  Acta Med Scand        ISSN: 0001-6101


  3 in total

Review 1.  Pathologic aspects of cirrhosis. A review.

Authors:  H Popper
Journal:  Am J Pathol       Date:  1977-04       Impact factor: 4.307

2.  Autoimmune hepatitis triggered by nitrofurantoin: a case series.

Authors:  Sally Appleyard; Ruma Saraswati; David A Gorard
Journal:  J Med Case Rep       Date:  2010-09-23

3.  Autoimmune hepatitis induced by nitrofurantoin. The importance of the autoantibodies for an early diagnosis of immune disease.

Authors:  Jagannath M Sherigar; Richard Fazio; Minsheng Zuang; Edward Arsura
Journal:  Clin Pract       Date:  2012-10-17
  3 in total

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