Literature DB >> 12585388

Studies towards the total synthesis of an epoxy isoprostane phospholipid, a potent activator of endothelial cells.

Michael E Jung1, Annika Kers, Ganesamoorthy Subbanagounder, Judith A Berliner.   

Abstract

We report studies toward the total synthesis of an epoxy isoprostane, namely the preparation of compound 9 which is an analogue of the elimination product 7 of the naturally occurring epoxy isoprostane 4 by a straightforward route using a three-component coupling, and have shown by several spectroscopic criteria that it closely resembles the natural material.

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Year:  2003        PMID： 12585388     DOI： 10.1039/b209892j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  Fatty acid epoxyisoprostane E2 stimulates an oxidative stress response in endothelial cells.

Authors:  Xinmin Yan; Sangderk Lee; B Gabriel Gugiu; Lukasz Koroniak; Michael E Jung; Judith Berliner; Jinluo Cheng; Rongsong Li
Journal:  Biochem Biophys Res Commun       Date:  2014-01-14       Impact factor: 3.575

2.  Palladium-catalyzed chemo- and enantioselective oxidation of allylic esters and carbonates.

Authors:  Barry M Trost; Jeffery Richardson; Kelvin Yong
Journal:  J Am Chem Soc       Date:  2006-03-01       Impact factor: 15.419

Review 3.  Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions.

Authors:  Simon C Dyall; Laurence Balas; Nicolas G Bazan; J Thomas Brenna; Nan Chiang; Felipe da Costa Souza; Jesmond Dalli; Thierry Durand; Jean-Marie Galano; Pamela J Lein; Charles N Serhan; Ameer Y Taha
Journal:  Prog Lipid Res       Date:  2022-05-01       Impact factor: 14.673
  3 in total

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