| Literature DB >> 12584135 |
Nickolai Alexandrov1, Ilya Shindyalov.
Abstract
UNLABELLED: We have developed a program for automatic identification of domains in protein three-dimensional structures. Performance of the program was assessed by three different benchmarks: (i) by comparison with the expert-curated SCOP database of structural domains; (ii) by comparison with a collection of manual domain assignments; and (iii) by comparison with a set of 55 proteins, frequently used as a benchmark for automatic domain assignment. In all these benchmarks PDP identified domains correctly in more than 80% of proteins. AVAILABILITY: http://123d.ncifcrf.gov/.Entities:
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Year: 2003 PMID: 12584135 DOI: 10.1093/bioinformatics/btg006
Source DB: PubMed Journal: Bioinformatics ISSN: 1367-4803 Impact factor: 6.937