OBJECTIVE: To observe the effects of Hovenia dulcis Thunb (HDT) on blood sugar and hepatic glycogen in diabetic mice. METHODS: The diabetes model was established by alloxan and treated with different doses of HDT for 7 days, while the positive control group was treated with glibenclamide. Then the blood sugar and hepatic glycogen were measured. RESULTS: The blood sugar of mice treated by HDT or glibenclamide significantly lower than diabetes model group. The hepatic glycogen in middle or low dose of HDT and glibenclamide groups was significantly increased. CONCLUSION: HDT has effect on lowing blood sugar and may become an effective anti-diabetic herb.
OBJECTIVE: To observe the effects of Hovenia dulcis Thunb (HDT) on blood sugar and hepatic glycogen in diabeticmice. METHODS: The diabetes model was established by alloxan and treated with different doses of HDT for 7 days, while the positive control group was treated with glibenclamide. Then the blood sugar and hepatic glycogen were measured. RESULTS: The blood sugar of mice treated by HDT or glibenclamide significantly lower than diabetes model group. The hepatic glycogen in middle or low dose of HDT and glibenclamide groups was significantly increased. CONCLUSION:HDT has effect on lowing blood sugar and may become an effective anti-diabetic herb.