| Literature DB >> 12582744 |
S Beltran1, Y Douadi, F X Lescure, M Hanau, G Laurans, J P Ducroix.
Abstract
This case report highlights the difficulty of diagnosing tuberculous sinusitis in the absence of pulmonary foci. Although extrapulmonary localisations of tuberculosis are rare in immunocompetent patients, it is important to consider this diagnosis, since therapeutic delay usually results in an unfavourable outcome. Acid-fast bacilli are sometimes difficult to detect in pathological specimens. Consequently, the diagnosis is usually based on the following criteria: (i) the absence of clinical response to usual antibiotics, (ii) the presence of caseous granulomatous inflammatory lesion on histopathology, and (iii) identification of Mycobacterium tuberculosis by the polymerase chain reaction assay confirmed by bacteriological culture. The diagnosis of tuberculosis is finally confirmed by the efficacy of antituberculous treatment. The differential diagnosis is Wegener's disease.Entities:
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Year: 2003 PMID: 12582744 DOI: 10.1007/s10096-002-0850-x
Source DB: PubMed Journal: Eur J Clin Microbiol Infect Dis ISSN: 0934-9723 Impact factor: 3.267