Literature DB >> 12582367

Clinical study of a spacer to help prevent osteoradionecrosis resulting from brachytherapy for tongue cancer.

Kenichi Obinata1, Keiichi Ohmori, Kazuhiko Tuchiya, Takeshi Nishioka, Hiroki Shirato, Motoyasu Nakamura.   

Abstract

OBJECTIVE: We sought to describe a simple method to construct a spacer and to evaluate with the use of computed tomography the spacer's effectiveness in preventing osteoradionecrosis of the mandible. STUDY
DESIGN: Fifty-three patients with oral tongue cancers who were treated by means of interstitial brachytherapy were included in this study. Patients underwent a computed tomography examination immediately after the implantation of radioactive sources, with the spacers in place. Distances between the radioactive sources and the lingual surfaces of the mandible were measured on transverse computed tomographs and were evaluated in terms of the development of osteoradionecrosis in the mandible.
RESULTS: Statistically significant differences in the frequency of osteoradionecrosis were observed between patients who had received spacers equal to or thicker than 5 mm and those who had received spacers less than 5 mm thick.
CONCLUSION: A spacer should have a minimum thickness of 5 mm on its lingual flange to prevent the development of osteoradionecrosis of the mandible.

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Mesh:

Year:  2003        PMID: 12582367     DOI: 10.1067/moe.2003.94

Source DB:  PubMed          Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod        ISSN: 1079-2104


  9 in total

Review 1.  The role of radioprotective spacers in clinical practice: a review.

Authors:  Qiuying Tang; Feng Zhao; Xiaokai Yu; Lingyun Wu; Zhongjie Lu; Senxiang Yan
Journal:  Quant Imaging Med Surg       Date:  2018-06

2.  Evaluation of radiodensity and dimensional stability of polymeric materials used for oral stents during external beam radiotherapy of head and neck carcinomas.

Authors:  Katarina Jonovic; Mutlu Özcan; Nadin Al-Haj Husain; Kiren Jan Mätzener; Ilja Frank Ciernik
Journal:  Clin Transl Radiat Oncol       Date:  2022-06-18

3.  Cesium implant for tongue carcinoma with a thickness of 1.5 cm or more: cases successfully treated with a Modified Manchester System.

Authors:  Takeshi Nishioka; Masaharu Fujino; Akihiro Homma; Tetsuro Yamashita; Akira Sato; Keiichi Ohmori; Kenichi Obinata; Hiroki Shirato; Kenichi Notani; Masamichi Nishio
Journal:  Yonsei Med J       Date:  2010-07       Impact factor: 2.759

4.  Experience of high-dose-rate brachytherapy for head and neck cancer treated by a customized intraoral mold technique.

Authors:  Kenichi Obinata; Keiichi Ohmori; Hiroki Shirato; Motoyasu Nakamura
Journal:  Radiat Med       Date:  2007-05-28

5.  Dosimetric analysis and clinical outcomes in CT-based mould brachytherapy in early oral cancers in patients unfit for surgery.

Authors:  Ashutosh Mukherji; Sinnatamby Mourougan; Kandasamy Saravannan; Singhavajala Vivekanandam; K Sathyanarayana Reddy
Journal:  J Contemp Brachytherapy       Date:  2015-04-01

6.  Designing and Dosimetry of a Shield for Photon Fields of Radiation Therapy in Oral Cavity Cancer.

Authors:  Keyvan Jabbari; Somayeh Senobari; Mahnaz Roayaei; Masoumeh Rostampour
Journal:  J Med Signals Sens       Date:  2015 Apr-Jun

7.  Preventing Complications from High-Dose Rate Brachytherapy when Treating Mobile Tongue Cancer via the Application of a Modular Lead-Lined Spacer.

Authors:  Shumei Murakami; Rinus G Verdonschot; Naoya Kakimoto; Iori Sumida; Masateru Fujiwara; Kazuhiko Ogawa; Souhei Furukawa
Journal:  PLoS One       Date:  2016-04-29       Impact factor: 3.240

8.  Laparoscopic Allograft Spacer Placement to Minimize Bowel Dose During Re-irradiation with Interstitial Brachytherapy.

Authors:  Shraddha Dalwadi; Anuj Suri; Aparna Kamat; E Brian Butler; Andrew M Farach
Journal:  Cureus       Date:  2019-10-22

9.  Spacers with boluses applied to various sites of oral squamous cell carcinoma: Technical note and retrospective case series.

Authors:  Kunio Yoshizawa; Shinichi Aoki; Kan Marino; Masaki Matsuda; Akinori Moroi; Koichiro Ueki
Journal:  Mol Clin Oncol       Date:  2021-07-13
  9 in total

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