Literature DB >> 12581777

Synthesis and anti-HIV activity of 2,3-diaryl-1,3-thiazolidin-4-ones.

Angela Rao1, Anna Carbone, Alba Chimirri, Erik De Clercq, Anna Maria Monforte, Pietro Monforte, Christophe Pannecouque, Maria Zappalà.   

Abstract

Several 1,3-thiazolidin-4-ones bearing a 2,6-dihalophenyl group at C-2 and a variously substituted phenyl ring at N-3 have been synthesized and tested as anti-HIV agents. The results of the in vitro tests showed that some of them proved to be effective inhibitors of HIV-1 replication. Copyright 2003 Editions scientifiques et médicales Elsevier SAS

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Year:  2003        PMID： 12581777     DOI： 10.1016/s0014-827x(02)00024-1

Source DB:  PubMed          Journal:  Farmaco        ISSN： 0014-827X


  2 in total

1.  New Biologically Hybrid Pharmacophore Thiazolidinone-Based Indole Derivatives: Synthesis, In Vitro Αlpha-Amylase and Αlpha-Glucosidase Along with Molecular Docking Investigations.

Authors:  Shoaib Khan; Shahid Iqbal; Fazal Rahim; Mazloom Shah; Rafaqat Hussain; Hamad Alrbyawi; Wajid Rehman; Ayed A Dera; Liaqat Rasheed; H H Somaily; Rami Adel Pashameah; Eman Alzahrani; Abd-ElAziem Farouk
Journal:  Molecules       Date:  2022-10-04       Impact factor: 4.927

2.  2-Heteroarylimino-5-arylidene-4-thiazolidinones as a new class of non-nucleoside inhibitors of HCV NS5B polymerase.

Authors:  Ilkay Küçükgüzel; Gökhan Satılmış; K R Gurukumar; Amartya Basu; Esra Tatar; Daniel B Nichols; Tanaji T Talele; Neerja Kaushik-Basu
Journal:  Eur J Med Chem       Date:  2013-09-12       Impact factor: 6.514
  2 in total

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