| Literature DB >> 12581616 |
Zahari Dimitrov Raikov1, Atanas Todorov Atanasov, Elena Todorova Raikova.
Abstract
Our studies showed that the spin-labeled (SL) compounds (free stable nitroxyl radical derivatives) accumulate predominantly in pigment melanoma and some of them possess high antimelanoma activity (100% curability of tumor bearing animals) and lower general toxicity. Taking into account our results we describe a proposed mechanism of the spin-labeled accumulation in melanoma, their antimelanoma activity and lower toxicity.Entities:
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Year: 2003 PMID： 12581616 DOI： 10.1016/s0306-9877(02)00407-3
Source DB: PubMed Journal: Med Hypotheses ISSN： 0306-9877 Impact factor: 1.538