Literature DB >> 12579098

Vacuum-assisted closure as a treatment modality for infections after cardiac surgery.

Heyman Luckraz1, Fiona Murphy, Steve Bryant, Susan C Charman, Andrew J Ritchie.   

Abstract

OBJECTIVE: Wound infections after cardiac surgery carry high morbidity and mortality. A plethora of management strategies have been used to treat such infections. We assessed the impact of vacuum-assisted closure on the management of sternal wound infections in terms of wound healing, duration of vacuum-assisted closure, and cost of treatment.
METHODS: Between November 1998 and June 2001, a total of 27 mediastinal infections were managed with vacuum-assisted closure. Group A (n = 14) had vacuum-assisted closure as the final treatment modality, whereas in group B (n = 13) vacuum-assisted closure was followed by either a myocutaneous flap (n = 8) or primary (n = 5) wound closure. The choice of additional treatment modality was based on wound size.
RESULTS: In group A, 4 patients died and a satisfactorily healed scar was achieved in 64% of cases. Median durations of vacuum-assisted closure and hospital stay in group A were 13.5 days (interquartile range 8.8-32.2 days) and 20 days (interquartile range 16.7-25.2 days), respectively. Mortality was 7.7% in group B, with a treatment failure rate of 15%. Median duration of vacuum-assisted closure in group B was 8 days (interquartile range 5.5-18 days), and median hospital stay was 29 days (interquartile range 25.8-38.2 days). During the year before institution of vacuum-assisted closure, poststernotomy infection (n = 13) was managed with rewiring and closed irrigation system. Treatment during this year failed in 30.7% of cases (n = 4/13), and mortality was also 30.7%. The total cost (hospitalization and treatment) per patient for vacuum-assisted closure was 16,400 dollars, compared with 20,000 dollars for the closed irrigation system treatment.
CONCLUSION: Vacuum-assisted closure, used alone or before other surgical treatment strategies, is an acceptable treatment modality for infections in cardiac surgery with reasonable morbidity, mortality, and cost.

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Year:  2003        PMID: 12579098     DOI: 10.1067/mtc.2003.74

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  22 in total

Review 1.  [The present state of vacuum sealing].

Authors:  J Tautenhahn; T Bürger; H Lippert
Journal:  Chirurg       Date:  2004-05       Impact factor: 0.955

2.  eComment. Vacuum-assisted closure therapy in cardiac surgery.

Authors:  Georgios Dimitrakakis; Agamemnon Pericleous; Dimitrios Challoumas; Inetzi A Dimitrakaki
Journal:  Interact Cardiovasc Thorac Surg       Date:  2012-01

3.  Assessment of vacuum-assisted closure therapy on the wound healing process in cardiac surgery.

Authors:  Agamemnon Pericleous; Georgios Dimitrakakis; Renos Photiades; Ulrich O von Oppell
Journal:  Int Wound J       Date:  2015-02-26       Impact factor: 3.315

4.  The management of deep sternal wound infections using vacuum assisted closure (V.A.C.) therapy.

Authors:  Tatjana Fleck; Ronny Gustafsson; Keith Harding; Richard Ingemansson; Mitchell D Lirtzman; Herbert L Meites; Reinhard Moidl; Patricia Price; Andrew Ritchie; Jorge Salazar; Johan Sjögren; David H Song; Bauer E Sumpio; Boulos Toursarkissian; Ferdinand Waldenberger; Walter Wetzel-Roth
Journal:  Int Wound J       Date:  2006-12       Impact factor: 3.315

Review 5.  Topical negative pressure therapy: mechanisms and indications.

Authors:  Paul E Banwell; Melinda Musgrave
Journal:  Int Wound J       Date:  2004-06       Impact factor: 3.315

Review 6.  [Vacuum-assisted closure therapy and wound coverage in soft tissue injury. Clinical use].

Authors:  G Holle; G Germann; M Sauerbier; K Riedel; H von Gregory; M Pelzer
Journal:  Unfallchirurg       Date:  2007-04       Impact factor: 1.000

7.  Haemodynamic effects of -75 mmHg negative pressure therapy in a porcine sternotomy wound model.

Authors:  Arash Mokhtari; Ronny Gustafsson; Johan Sjögren; Johan Nilsson; Sandra Lindstedt; Malin Malmsjö; Richard Ingemansson
Journal:  Int Wound J       Date:  2009-02       Impact factor: 3.315

Review 8.  Topical negative pressure wound therapy: a review of its role and guidelines for its use in the management of acute wounds.

Authors:  Estas Bovill; Paul E Banwell; Luc Teot; Elof Eriksson; Colin Song; Jim Mahoney; Ronny Gustafsson; Raymund Horch; Anand Deva; Ian Whitworth
Journal:  Int Wound J       Date:  2008-09-19       Impact factor: 3.315

Review 9.  Vacuum-assisted closure home care training: a process to link education to improved patient outcomes.

Authors:  Kevin Y Woo; R Gary Sibbald
Journal:  Int Wound J       Date:  2008-06       Impact factor: 3.315

10.  Vacuum-assisted closure in the treatment of perineal necrotizing skin and soft tissue infections.

Authors:  Régis Bronchard; Cyrille de Vaumas; Sigismond Lasocki; Khalil Jabbour; Arnaud Geffroy; Nathalie Kermarrec; Philippe Montravers
Journal:  Intensive Care Med       Date:  2008-04-04       Impact factor: 17.440

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