Literature DB >> 1257784

Rapid discrimination of rewarding nutrient by the upper gastrointestinal tract.

A Puerto, J A Deutsch, F Mólina, P L Roll.   

Abstract

When certain nutrients are injected into the stomachs of rats that are drinking one of two samples of nonnutrient, flavored water, the rats will (within a 10-minute session) choose the flavor paired with the nutrient. Such rewarding effects have obtained with predigested milk but not with similarly treated glucose or fresh milk. The results suggest the presence of rapidly acting, specialized, nutrient receptors in the upper gastrointestinal tract.

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Year:  1976        PMID: 1257784     DOI: 10.1126/science.1257784

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  6 in total

Review 1.  Gut-brain nutrient signaling. Appetition vs. satiation.

Authors:  Anthony Sclafani
Journal:  Appetite       Date:  2012-06-01       Impact factor: 3.868

2.  Conditioned place preference induced by electrical stimulation of the insular cortex: effects of naloxone.

Authors:  Raquel García; María J Simón; Amadeo Puerto
Journal:  Exp Brain Res       Date:  2013-02-02       Impact factor: 1.972

3.  Rapid post-oral stimulation of intake and flavor conditioning by glucose and fat in the mouse.

Authors:  Steven Zukerman; Karen Ackroff; Anthony Sclafani
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2011-10-05       Impact factor: 3.619

Review 4.  The neural basis of sugar preference.

Authors:  Winston W Liu; Diego V Bohórquez
Journal:  Nat Rev Neurosci       Date:  2022-07-25       Impact factor: 38.755

5.  Rapid post-oral stimulation of intake and flavor conditioning in rats by glucose but not a non-metabolizable glucose analog.

Authors:  Karen Ackroff; Anthony Sclafani
Journal:  Physiol Behav       Date:  2014-05-06

6.  Intravascular food reward.

Authors:  Albino J Oliveira-Maia; Craig D Roberts; Q David Walker; Brooke Luo; Cynthia Kuhn; Sidney A Simon; Miguel A L Nicolelis
Journal:  PLoS One       Date:  2011-09-27       Impact factor: 3.240

  6 in total

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