Literature DB >> 12577773

[The clinical diagnosis 'wound botulism' in an injecting drug addict].

R S Rundervoort1, A J A M van der Ven, C Vermeulen, R J van Oostenbrugge.   

Abstract

A 38-year-old subcutaneous injecting heroin addict had subacute blurred vision, dysarthria and dysphagia. The next day she could not swallow or speak and developed weakness of all limbs and respiratory failure. Electromyography showed abnormalities compatible with a presynaptic neuromuscular transmission deficit, which supported the diagnosis of botulism. The point of entry was probably a skin abscess due to injections. Treatment with antitoxin and antibiotics resulted in a favourable recovery. Wound botulism is caused by local production of toxin by Clostridium botulinum after wound infection. Although it is a rare variant of botulism, it is increasingly being reported in drug users who inject subcutaneously.

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Year:  2003        PMID: 12577773

Source DB:  PubMed          Journal:  Ned Tijdschr Geneeskd        ISSN: 0028-2162


  1 in total

1.  A decade of spore-forming bacterial infections among European injecting drug users: pronounced regional variation.

Authors:  Vivian D Hope; Norah Palmateer; Lucas Wiessing; Andrea Marongiu; Joanne White; Fortune Ncube; David Goldberg
Journal:  Am J Public Health       Date:  2011-11-28       Impact factor: 9.308

  1 in total

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