Literature DB >> 1257757

Tin: a potent inducer of heme oxygenase in kidney.

A Kappas, M D Maines.   

Abstract

Tin greatly enhances heme breakdown in kidney, thus impairing heme-dependent cellular functions, such as cytochrome P-450 mediated drug biotransformation. This novel action of the metal results from a potent induction effect on heme oxygenase, the enzyme that catalyzes heme oxidation in microsomes. The possible toxicological implications of this tin effect in the kidney merit further investigation.

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Year:  1976        PMID： 1257757     DOI： 10.1126/science.1257757

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  23 in total

1.  Recovery from stress is a function of age and telomere length.

Authors:  Graham M Strub; Amy Depcrynski; Lynne W Elmore; Shawn E Holt
Journal:  Cell Stress Chaperones       Date:  2008-05-20       Impact factor: 3.667

Review 2.  Control of heme metabolism with synthetic metalloporphyrins.

Authors:  A Kappas; G S Drummond
Journal:  J Clin Invest       Date:  1986-02       Impact factor: 14.808

3.  Effects of heat shock, stannous chloride, and gallium nitrate on the rat inflammatory response.

Authors:  S D House; P T Guidon; G A Perdrizet; M Rewinski; R Kyriakos; R S Bockman; T Mistry; R A Gallagher; L E Hightower
Journal:  Cell Stress Chaperones       Date:  2001-04       Impact factor: 3.667

4.  Hepatic metabolism of heme in rats after exposure to benzene, gasoline and kerosene.

Authors:  G S Rao; K P Pandya
Journal:  Arch Toxicol       Date:  1980-12       Impact factor: 5.153

5.  Prolonged induction of hepatic haem oxygenase and decreases in cytochrome P-450 content by organotin compounds.

Authors:  D W Rosenberg; G S Drummond; H C Cornish; A Kappas
Journal:  Biochem J       Date:  1980-08-15       Impact factor: 3.857

6.  Induction of liver cell haem oxygenase in iron-overloaded rats.

Authors:  N G Ibrahim; S T Hoffstein; M L Freedman
Journal:  Biochem J       Date:  1979-05-15       Impact factor: 3.857

7.  Selenium regulation of hepatic heme metabolism: induction of delta-aminolevulinate synthase and heme oxygenase.

Authors:  M D Maines; A Kappas
Journal:  Proc Natl Acad Sci U S A       Date:  1976-12       Impact factor: 11.205

8.  Manganese and zinc blockade of enzyme induction: studies with microsomal heme oxygenase.

Authors:  G S Drummond; A Kappas
Journal:  Proc Natl Acad Sci U S A       Date:  1979-10       Impact factor: 11.205

9.  Disturbances in heme biosynthesis in rabbits after administration per os of low doses of tin or lead.

Authors:  G Zareba; J Chmielnicka
Journal:  Biol Trace Elem Res       Date:  1992-08       Impact factor: 3.738

Review 10.  The elementome of calcium-based urinary stones and its role in urolithiasis.

Authors:  Krishna Ramaswamy; David W Killilea; Pankaj Kapahi; Arnold J Kahn; Thomas Chi; Marshall L Stoller
Journal:  Nat Rev Urol       Date:  2015-09-01       Impact factor: 14.432
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