| Literature DB >> 12575943 |
Abstract
The exocyst is an octameric complex mediating vesicle targeting and tethering at the plasma membrane for exocytosis. The role of exocyst in nervous system is unclear. In this issue of Neuron, Murthy et al. provide important insights: defects in the exocyst inhibit neurite outgrowth and neuromuscular junction formation; however, synaptic transmission persists.Mesh:
Year: 2003 PMID: 12575943 DOI: 10.1016/s0896-6273(03)00059-x
Source DB: PubMed Journal: Neuron ISSN: 0896-6273 Impact factor: 17.173