Literature DB >> 12573691

Molecular radio jamming: autoinducer analogs.

Walter Fast1.   

Abstract

Synthesis of an N-acyl-homoserine lactone (N-acyl-HSL) analog library yields agonists and antagonists of the Pseudomonas aeruginosa quorum-sensing system. Active compounds also reveal heterogeneity in the lactone ring binding pockets of N-acyl-HSL-activated transcription factors.

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Year:  2003        PMID: 12573691     DOI: 10.1016/s1074-5521(03)00005-x

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  1 in total

1.  Panax ginseng has anti-infective activity against opportunistic pathogen Pseudomonas aeruginosa by inhibiting quorum sensing, a bacterial communication process critical for establishing infection.

Authors:  Z Song; K F Kong; H Wu; N Maricic; B Ramalingam; H Priestap; L Schneper; J M E Quirke; N Høiby; K Mathee
Journal:  Phytomedicine       Date:  2010-11       Impact factor: 5.340

  1 in total

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