Literature DB >> 12573438

Telomeres and cancer: a tale with many endings.

María A Blasco1.   

Abstract

Telomerase activity is necessary to maintain the integrity of telomeres, which in turn prevent chromosome ends from being processed and signaled as damaged DNA. That cancer cells rely on telomerase to maintain functional telomeres and to divide indefinitely has highlighted the potential for developing novel therapeutic approaches that target telomerase.

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Year:  2003        PMID： 12573438     DOI： 10.1016/s0959-437x(02)00011-4

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN： 0959-437X            Impact factor:   5.578


  20 in total

1.  Molecular cross-talk among chromosome fragility syndromes.

Authors:  Jordi Surrallés; Stephen P Jackson; Maria Jasin; Michael B Kastan; Stephen C West; Hans Joenje
Journal:  Genes Dev       Date:  2004-06-15       Impact factor: 11.361

2.  Mitogen-activated protein kinase cascade-mediated histone H3 phosphorylation is critical for telomerase reverse transcriptase expression/telomerase activation induced by proliferation.

Authors:  Zheng Ge; Cheng Liu; Magnus Björkholm; Astrid Gruber; Dawei Xu
Journal:  Mol Cell Biol       Date:  2006-01       Impact factor: 4.272

3.  Genes and pathways downstream of telomerase in melanoma metastasis.

Authors:  Sepideh Bagheri; Mehdi Nosrati; Shang Li; Sylvia Fong; Sima Torabian; Javier Rangel; Dan H Moore; Scot Federman; Rebecca R Laposa; Frederick L Baehner; Richard W Sagebiel; James E Cleaver; Christopher Haqq; Robert J Debs; Elizabeth H Blackburn; Mohammed Kashani-Sabet
Journal:  Proc Natl Acad Sci U S A       Date:  2006-07-17       Impact factor: 11.205

4.  The biological activity of G-quadruplex DNA binding papaverine-derived ligand in breast cancer cells.

Authors:  Blazej Rubis; Mariusz Kaczmarek; Natalia Szymanowska; Elzbieta Galezowska; Andrzej Czyrski; Bernard Juskowiak; Tadeusz Hermann; Maria Rybczynska
Journal:  Invest New Drugs       Date:  2008-09-05       Impact factor: 3.850

5.  Assembly mechanisms of RNA pseudoknots are determined by the stabilities of constituent secondary structures.

Authors:  Samuel S Cho; David L Pincus; D Thirumalai
Journal:  Proc Natl Acad Sci U S A       Date:  2009-10-05       Impact factor: 11.205

Review 6.  Entropic stabilization of the folded states of RNA due to macromolecular crowding.

Authors:  Natalia A Denesyuk; D Thirumalai
Journal:  Biophys Rev       Date:  2013-04-18

7.  Mapping the FEN1 interaction domain with hTERT.

Authors:  Shilpa Sampathi; Weihang Chai
Journal:  Biochem Biophys Res Commun       Date:  2011-02-21       Impact factor: 3.575

8.  Transfecting RNA quadruplexes results in few transcriptome perturbations.

Authors:  Phil G T Sanders; James Cotterell; James Sharpe; Mark Isalan
Journal:  RNA Biol       Date:  2012-12-12       Impact factor: 4.652

9.  Pyrimidine motif triple helix in the Kluyveromyces lactis telomerase RNA pseudoknot is essential for function in vivo.

Authors:  Darian D Cash; Osnat Cohen-Zontag; Nak-Kyoon Kim; Kinneret Shefer; Yogev Brown; Nikolai B Ulyanov; Yehuda Tzfati; Juli Feigon
Journal:  Proc Natl Acad Sci U S A       Date:  2013-06-17       Impact factor: 11.205

10.  Constitutive expression of tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-Tert mice.

Authors:  Andrés Canela; Juan Martín-Caballero; Juana M Flores; María A Blasco
Journal:  Mol Cell Biol       Date:  2004-05       Impact factor: 4.272
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