Literature DB >> 12572506

[Protective effect of paeonol on repeated cerebral ischemia in rats].

G Zhang1, Z Yu, H Zhao.   

Abstract

Protcective effect of paeonol was observed in the repeated cerebral ischemia-reperfusion model in rats. Paeonol (100, 50 mg/kg x 7 d i.p.) could inhibit the increase of Ca2+, the decrease of superoxide dimutase (SOD) activity and the content of malondialdehyde (MDA), improve Ca(2+)-ATPase activity in ischemia brain tissue. The results showed that paeonol could protect cerebral ischemia by inhibiting accumulation of Ca2+ and production of oxygen free radical.

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Year:  1997        PMID： 12572506

Source DB:  PubMed          Journal:  Zhong Yao Cai        ISSN： 1001-4454


  10 in total

Review 1.  Chinese medicines and bioactive compounds for treatment of stroke.

Authors:  Thanasekaran Jayakumar; Antoinet Ramola Elizebeth; Ting-lin Yen; Joen-rong Sheu
Journal:  Chin J Integr Med       Date:  2014-07-10       Impact factor: 1.978

2.  Paeonol induces vasodilatation in rat mesenteric artery via inhibiting extracellular Ca²⁺ influx and intracellular Ca²⁺ release.

Authors:  Jin-Yan Zhang; Yong-Xiao Cao; Wei-Liang Weng; Yi-Kui Li; Le Zhao
Journal:  Chin J Integr Med       Date:  2013-07-02       Impact factor: 1.978

3.  Anticonvulsant and Neuroprotective Effects of Paeonol in Epileptic Rats.

Authors:  Dong-Hai Liu; Elvis Agbo; Shu-Hong Zhang; Jin-Ling Zhu
Journal:  Neurochem Res       Date:  2019-09-13       Impact factor: 3.996

4.  Paeonol oxime inhibits bFGF-induced angiogenesis and reduces VEGF levels in fibrosarcoma cells.

Authors:  Hyo-Jeong Lee; Seung-Ae Kim; Hyo-Jung Lee; Soo-Jin Jeong; Ihn Han; Ji Hoon Jung; Eun-Ok Lee; Shudong Zhu; Chang-Yan Chen; Sung-Hoon Kim
Journal:  PLoS One       Date:  2010-08-23       Impact factor: 3.240

5.  Anti-inflammatory effects of Chinese medicinal herbs on cerebral ischemia.

Authors:  Shan-Yu Su; Ching-Liang Hsieh
Journal:  Chin Med       Date:  2011-07-09       Impact factor: 5.455

6.  In situ and in vivo study of nasal absorption of paeonol in rats.

Authors:  Xiaolan Chen; Yang Lu; Shouying Du; Bing Xu; Shan Wang; Yongsong Zhai; Xiao Song; Pengyue Li
Journal:  Int J Mol Sci       Date:  2010-11-26       Impact factor: 5.923

7.  Screening of bioactive compounds from moutan cortex and their anti-inflammatory activities in rat synoviocytes.

Authors:  Mengjie Wu; Zhiyuan Gu
Journal:  Evid Based Complement Alternat Med       Date:  2007-06-15       Impact factor: 2.629

8.  Ligusticum wallichii Extract Inhibited the Expression of IL-1β after AMI in Rats.

Authors:  Zhuo Yuan; Junping Zhang; Cui Yang
Journal:  Evid Based Complement Alternat Med       Date:  2014-08-17       Impact factor: 2.629

9.  Paeonol Protects Rat Heart by Improving Regional Blood Perfusion during No-Reflow.

Authors:  Lina Ma; Chia-Chen Chuang; Weiliang Weng; Le Zhao; Yongqiu Zheng; Jinyan Zhang; Li Zuo
Journal:  Front Physiol       Date:  2016-07-21       Impact factor: 4.566

Review 10.  Ameliorating effects of traditional Chinese medicine preparation, Chinese materia medica and active compounds on ischemia/reperfusion-induced cerebral microcirculatory disturbances and neuron damage.

Authors:  Kai Sun; Jingyu Fan; Jingyan Han
Journal:  Acta Pharm Sin B       Date:  2015-01-24       Impact factor: 11.413
  10 in total

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