Literature DB >> 12570863

Iminosugars and relatives as antiviral and potential anti-infective agents.

P Greimel1, J Spreitz, A E Stütz, T M Wrodnigg.   

Abstract

Iminosugars have emerged in the literature during mid-1960's as synthetic compounds. Around the same time, the first examples were found in Nature and their interesting enzyme inhibitory properties were recognised. Due to their powerful interference with glycohydrolases (glycosidases) as well as glycosyltransferases, quite a few representatives exhibit notable biological activities. These range from anti-diabetic, insect antifeedant, nematicidal, plant growth regulating to immunomodulating, anti-cancer as well as - in selected cases - anti-infective properties. The latter will be the focus of the following survey.

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Year:  2003        PMID： 12570863     DOI： 10.2174/1568026033452456

Source DB:  PubMed          Journal:  Curr Top Med Chem        ISSN： 1568-0266            Impact factor:   3.295


  9 in total

1.  PDIA, an Iminosugar Compound with a Wide Biofilm Inhibitory Spectrum Covering Both Gram-Positive and Gram-Negative Human Bacterial Pathogens.

Authors:  Łucja Kozień; Estelle Gallienne; Olivier Martin; Sophie Front; Magdalena Strus; Piotr Heczko
Journal:  Microorganisms       Date:  2022-06-15

2.  Synthesis of (R)-dihydropyridones as key intermediates for an efficient access to piperidine alkaloids.

Authors:  Evangelia N Tzanetou; Konstantinos M Kasiotis; Prokopios Magiatis; Serkos A Haroutounian
Journal:  Molecules       Date:  2007-04-10       Impact factor: 4.411

3.  Metathesis access to monocyclic iminocyclitol-based therapeutic agents.

Authors:  Ileana Dragutan; Valerian Dragutan; Carmen Mitan; Hermanus Cm Vosloo; Lionel Delaude; Albert Demonceau
Journal:  Beilstein J Org Chem       Date:  2011-05-27       Impact factor: 2.883

4.  N-Nonyloxypentyl-l-Deoxynojirimycin Inhibits Growth, Biofilm Formation and Virulence Factors Expression of Staphylococcus aureus.

Authors:  Eliana De Gregorio; Anna Esposito; Adriana Vollaro; Maria De Fenza; Daniele D'Alonzo; Antonella Migliaccio; Vita Dora Iula; Raffaele Zarrilli; Annalisa Guaragna
Journal:  Antibiotics (Basel)       Date:  2020-06-26

5.  Identification of Novel Human Breast Carcinoma (MDA-MB-231) Cell Growth Modulators from a Carbohydrate-Based Diversity Oriented Synthesis Library.

Authors:  Elena Lenci; Riccardo Innocenti; Alessio Biagioni; Gloria Menchi; Francesca Bianchini; Andrea Trabocchi
Journal:  Molecules       Date:  2016-10-20       Impact factor: 4.411

6.  Toward the Identification of Novel Antimicrobial Agents: One-Pot Synthesis of Lipophilic Conjugates of N-Alkyl d- and l-Iminosugars.

Authors:  Anna Esposito; Daniele D'Alonzo; Stefano D'Errico; Eliana De Gregorio; Annalisa Guaragna
Journal:  Mar Drugs       Date:  2020-11-19       Impact factor: 5.118

7.  Synthesis of Functionalized Azepines via Cu(I)-Catalyzed Tandem Amination/Cyclization Reaction of Fluorinated Allenynes.

Authors:  Anna N Philippova; Daria V Vorobyeva; Pavel S Gribanov; Ivan A Godovikov; Sergey N Osipov
Journal:  Molecules       Date:  2022-08-15       Impact factor: 4.927

8.  A new approach toward the total synthesis of (+)-batzellaside B.

Authors:  Jolanta Wierzejska; Shin-Ichi Motogoe; Yuto Makino; Tetsuya Sengoku; Masaki Takahashi; Hidemi Yoda
Journal:  Beilstein J Org Chem       Date:  2012-10-25       Impact factor: 2.883

9.  Protecting-group-free synthesis of 2-deoxy-aza-sugars.

Authors:  Emma Marie Dangerfield; Catherine Heather Plunkett; Bridget Louise Stocker; Mattie Simon Maria Timmer
Journal:  Molecules       Date:  2009-12-16       Impact factor: 4.411
  9 in total

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