Literature DB >> 12569310

Spiral hydro-CT in the evaluation of colo-sigmoideal cancer.

Filippo Cademartiri1, Giacomo Luccichenti, Armando Rossi, Paolo Pavone.   

Abstract

PURPOSE: To evaluate the accuracy of spiral hydro-CT in the diagnosis and preoperative staging of colo-sigmoideal neoplasms and the impact of this technique on therapeutic decisions.
MATERIALS AND METHODS: Sixty patients with colo-sigmoideal neoplasms, 16 in caecum-ascending colon, 2 in transverse colon, 14 in descending colon, and 28 in sigmoid colon, diagnosed with fiberoptic colonoscopy and histopathological specimen, under-went spiral hydro-CT with IV contrast medium administration. Local invasion (T factor) and nodal involvement (N factor) were evaluated. In all cases, the CT reports were compared with the result of the histopathological examination of the surgical specimen. TNM and Dukes staging classifications were applied.
RESULTS: Local invasion was correctly identified in 80% of cases. There was overstaging in 18.3% and understaging in 1.7% of the patients. Sensitivity, specificity and accuracy for nodal involvement were 57.9%, 67.5% and 63.3%, respectively. There was overstaging in 23.3% and understaging in 15% of patients. With Dukes classification, CT correctly staged 38.8% of patients. Significant differences were detected in different stages. The stage with the highest concordance was A/B1 with 58.8% (10/17), whereas the one with the lowest concordance was B2 with 9.1% (2/22). All of the three patients in stage D were correctly staged and none of the patients with stage C was overstaged.
CONCLUSIONS: Spiral hydro-CT with intravenous contrast medium administration, despite the limits in the correct evaluation of local depth invasion and nodal involvement, proved useful for selecting patients likely to benefit from surgery.

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Year:  2002        PMID: 12569310

Source DB:  PubMed          Journal:  Radiol Med        ISSN: 0033-8362            Impact factor:   3.469


  4 in total

1.  Preoperative local staging of colosigmoideal cancer: air versus water multidetector-row CT colonography.

Authors:  A A Stabile Ianora; M Moschetta; P Pedote; A Scardapane; G Angelelli
Journal:  Radiol Med       Date:  2012-01-21       Impact factor: 3.469

2.  The role of multidetector CT in local staging and evaluation of retroperitoneal surgical margin involvement in colon cancer.

Authors:  Funda Dinç Elibol; Funda Obuz; Selman Sökmen; Cem Terzi; Aras Emre Canda; Özgül Sağol; Sülen Sarıoğlu
Journal:  Diagn Interv Radiol       Date:  2016 Jan-Feb       Impact factor: 2.630

3.  The Correlation between 18F-FDG PET/CT Imaging SUVmax of Preoperative Colon Cancer Primary Lesions and Clinicopathological Factors.

Authors:  Dacheng Li; Ying Wang; Weili Liu; Qiusong Chen; Li Cai; Xiling Xing; Shuo Gao
Journal:  J Oncol       Date:  2021-09-17       Impact factor: 4.375

4.  Phase 2 study of perioperative chemotherapy with SOX and surgery for stage III colorectal cancer (SOS3 study).

Authors:  Naoya Aisu; Yoichiro Yoshida; Akira Komono; Ryohei Sakamoto; Daibo Kojima; Suguru Hasegawa
Journal:  Sci Rep       Date:  2019-11-12       Impact factor: 4.379

  4 in total

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