OBJECTIVE: To investigate the effect of cigarette smoking on main sperm variables. DESIGN: Cohort study. SETTING: Men attending the andrology laboratory in the context of infertility investigation in the couple. PATIENT(S): Eight hundred thirty-nine smokers and 1,266 non-smokers were enrolled; 655 smokers and 1,131 nonsmokers fulfilled the inclusion criteria and were compared. Standard clinical analysis of semen. RESULT(S): Cigarette smoking was associated with a significant decrease in sperm density (-15.3%), total sperm count (-17.5%), total number of motile sperm (-16.6%), and citrate concentration (-22.4%). The percentage of normal forms was significantly reduced in smokers, and sperm vitality, ejaculate volume, and fructose concentration were slightly but nonsignificantly affected. CONCLUSION(S): Cigarette smoking is associated with reduced semen quality.
OBJECTIVE: To investigate the effect of cigarette smoking on main sperm variables. DESIGN: Cohort study. SETTING:Men attending the andrology laboratory in the context of infertility investigation in the couple. PATIENT(S): Eight hundred thirty-nine smokers and 1,266 non-smokers were enrolled; 655 smokers and 1,131 nonsmokers fulfilled the inclusion criteria and were compared. Standard clinical analysis of semen. RESULT(S): Cigarette smoking was associated with a significant decrease in sperm density (-15.3%), total sperm count (-17.5%), total number of motile sperm (-16.6%), and citrate concentration (-22.4%). The percentage of normal forms was significantly reduced in smokers, and sperm vitality, ejaculate volume, and fructose concentration were slightly but nonsignificantly affected. CONCLUSION(S): Cigarette smoking is associated with reduced semen quality.
Authors: Tina Kold Jensen; Shanna Swan; Niels Jørgensen; Jorma Toppari; Bruce Redmon; Margus Punab; Erma Z Drobnis; Trine Berit Haugen; Birute Zilaitiene; Amy E Sparks; D Stewart Irvine; Christina Wang; Pierre Jouannet; Charlene Brazil; Uwe Paasch; Andrea Salzbrunn; Niels Erik Skakkebæk; Anna-Maria Andersson Journal: Hum Reprod Date: 2014-06-03 Impact factor: 6.918