OBJECTIVE: To determine the effect of Schistosoma japonicum infection on the testoterone level in the sera from male C57BL/6 mice. METHODS: Radioimmunoassay was used to examine testosterone levels in sera of 9 male mice experimentally infected with Schistosoma japonicum. RESULTS: The serum testosterone levels reduced significantly in all experimentally infected animals 45 days after infection, as compared with the uninfected controls. CONCLUSION: Infection with Schistosoma japonicum decreases testosterone levels in the mouse host.
OBJECTIVE: To determine the effect of Schistosoma japonicum infection on the testoterone level in the sera from male C57BL/6 mice. METHODS: Radioimmunoassay was used to examine testosterone levels in sera of 9 male mice experimentally infected with Schistosoma japonicum. RESULTS: The serum testosterone levels reduced significantly in all experimentally infected animals 45 days after infection, as compared with the uninfected controls. CONCLUSION: Infection with Schistosoma japonicum decreases testosterone levels in the mouse host.