| Literature DB >> 12567281 |
Im Seon Lee, Hyeong-Kyu Lee, Nguyen Tien Dat, Mi Sun Lee, Jung Woo Kim, Doe Sun Na, Young Ho Kim.
Abstract
Seven lignans from Schisandra chinensis were investigated for their inhibitory activity on NFAT transcription. Both gomisin N (IC 50 : 1.33 +/- 0.05 microM) and schisandrol A (IC 50 : 1.34 +/- 0.05 microM) showed higher activity than gomisin E (IC 50 : 4.73 +/- 0.09 microM), schisandrin A (IC 50 : 7.23 +/- 0.21 microM), schisandrin C (IC 50 : 7.54 +/- 0.22 microM), benzoylisogomisin O (IC 50 : 11.06 +/- 1.02 microM) and schisandrol B (IC 50 : 16.37 +/- 1.00 microM).Entities:
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Year: 2003 PMID： 12567281 DOI： 10.1055/s-2003-37024
Source DB: PubMed Journal: Planta Med ISSN： 0032-0943 Impact factor: 3.352