Literature DB >> 12564784

Benefits of combination vaccines: effective vaccination on a simplified schedule.

Daisy Dodd.   

Abstract

BACKGROUND: The number of recommended immunizations during childhood has increased significantly over the years. Today, infants receive vaccines against 11 diseases in the first 2 years of life, and may receive as many as 5 injections at a single office visit. For a number of reasons, some injections may be deferred to a later visit, thus creating a missed opportunity for vaccination.
OBJECTIVE: To review benefits of pediatric combination vaccines.
RESULTS: Combination vaccines that protect against several diseases, such as the new DTaP-HepB-IPV (Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Hepatitis B [Recom-binant] and Inactivated Poliovirus Vaccine Combined) vaccine, can help to simplify the current immunization schedule. Other benefits of combination vaccines for parents and healthcare providers include decreased anxiety because of perceived reduction in pain for the infant, fewer missed opportunities to vaccinate, convenience, and decreased costs for the parent as a result of fewer office visits. Benefits of using combination vaccines in the office setting include reduced missed opportunities to vaccinate, storage of fewer vials, decreased risk of needle sticks as a result of handling fewer syringes, and potentially improved record keeping and tracking. Benefits of using combination vaccines in managed care include improved member satisfaction and lower costs because of fewer vaccine administration charges, and potentially fewer office visits.
CONCLUSIONS: Combination vaccines are an effective means of decreasing the number of injections and simplifying the immunization schedule, thus providing overall benefits to infants, parents, healthcare providers, office managers, and managed care administrators.

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Year:  2003        PMID: 12564784

Source DB:  PubMed          Journal:  Am J Manag Care        ISSN: 1088-0224            Impact factor:   2.229


  19 in total

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2.  A web-based tool for designing vaccine formularies for childhood immunization in the United States.

Authors:  Sheldon H Jacobson; Edward C Sewell
Journal:  J Am Med Inform Assoc       Date:  2008-06-25       Impact factor: 4.497

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4.  Comparison of the tolerability of newly introduced childhood vaccines in the Netherlands.

Authors:  Jeanet M Kemmeren; Nicoline At van der Maas; Hester E de Melker
Journal:  Eur J Pediatr       Date:  2017-04-20       Impact factor: 3.183

5.  Age-appropriate compliance and completion of up to five doses of pertussis vaccine in US children.

Authors:  Girishanthy Krishnarajah; Elisabetta Malangone-Monaco; Liisa Palmer; Ellen Riehle; Philip O Buck
Journal:  Hum Vaccin Immunother       Date:  2018-08-29       Impact factor: 3.452

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7.  Immunogenicity and Reactogenicity following Primary Immunisation with a Combined DTaP-HBV Vaccine and a Haemophilus influenzae Type B Vaccine Administered by Separate or Mixed Injection.

Authors:  G Gabutti; G Bona; P Dentico; F Bamfi; K Hardt; S Majori; P Crovari
Journal:  Clin Drug Investig       Date:  2005       Impact factor: 2.859

8.  Combination vaccine against invasive meningococcal B and pneumococcal infections: potential epidemiological and economic impact in the Netherlands.

Authors:  Jasper M Bos; Hans C Rümke; Robert Welte; Lodewijk Spanjaard; Loek van Alphen; Maarten J Postma
Journal:  Pharmacoeconomics       Date:  2006       Impact factor: 4.981

9.  Parental reports of adverse events following simultaneously given dT-IPV and MMR vaccines in healthy 9-year-old children.

Authors:  Jeanet M Kemmeren; Nicoline A T van der Maas; Hester E de Melker
Journal:  Eur J Pediatr       Date:  2010-09-21       Impact factor: 3.860

10.  Immunogenicity and safety of a tetravalent measles-mumps-rubella-varicella vaccine: an open-labeled, randomized trial in healthy Korean children.

Authors:  Sung-Ho Cha; Seon-Hee Shin; Taek-Jin Lee; Chang Hwi Kim; Michael Povey; Hwang Min Kim; Ouzama Nicholson
Journal:  Clin Exp Vaccine Res       Date:  2013-12-18
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