Literature DB >> 12562087

Antibacterial diterpenoids from Astragalus brachystachys.

Amir Reza Jassbi1, Simin Zamanizadehnajari, Parviz Aberoomand Azar, Satoshi Tahara.   

Abstract

Antibacterial bioassay guided fractionation of acetone extracts of Astragalus brachystachys resulted in isolation of sclareol and two related labdane-type diterpenoids, 14R-epoxysclareol and 6beta-hydroxysclareol. The antibacterial activity of the isolated compounds was measured and it was deduced that the epoxidation at the double bond of sclareol or hydroxylation at C-6 decreased the activity of the resulting compounds. Salvigenin (5-hydroxy-4',6,7-trimethoxyflavone) was also separated from this plant for the first time.

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Year:  2002        PMID： 12562087     DOI： 10.1515/znc-2002-11-1211

Source DB:  PubMed          Journal:  Z Naturforsch C J Biosci        ISSN： 0341-0382


  8 in total

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Review 6.  Flavonoids from the Genus Astragalus: Phytochemistry and Biological Activity.

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  8 in total

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