Literature DB >> 12560456

Demystified. Human endogenous retroviruses.

P N Nelson1, P R Carnegie, J Martin, H Davari Ejtehadi, P Hooley, D Roden, S Rowland-Jones, P Warren, J Astley, P G Murray.   

Abstract

Human endogenous retroviruses (HERVs) are a family of viruses within our genome with similarities to present day exogenous retroviruses. HERVs have been inherited by successive generations and it is possible that some have conferred biological benefits. However, several HERVs have been implicated in certain cancers and autoimmune diseases. This article demystifies these retroviruses by providing an insight into HERVs, their means of classification, and a synopsis of HERVs implicated in cancer and autoimmunity. Furthermore, the biological roles of HERVs are explored.

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Year:  2003        PMID: 12560456      PMCID: PMC1187282          DOI: 10.1136/mp.56.1.11

Source DB:  PubMed          Journal:  Mol Pathol        ISSN: 1366-8714


  81 in total

1.  Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes.

Authors:  M Speek
Journal:  Mol Cell Biol       Date:  2001-03       Impact factor: 4.272

2.  Initial sequencing and analysis of the human genome.

Authors:  E S Lander; L M Linton; B Birren; C Nusbaum; M C Zody; J Baldwin; K Devon; K Dewar; M Doyle; W FitzHugh; R Funke; D Gage; K Harris; A Heaford; J Howland; L Kann; J Lehoczky; R LeVine; P McEwan; K McKernan; J Meldrim; J P Mesirov; C Miranda; W Morris; J Naylor; C Raymond; M Rosetti; R Santos; A Sheridan; C Sougnez; Y Stange-Thomann; N Stojanovic; A Subramanian; D Wyman; J Rogers; J Sulston; R Ainscough; S Beck; D Bentley; J Burton; C Clee; N Carter; A Coulson; R Deadman; P Deloukas; A Dunham; I Dunham; R Durbin; L French; D Grafham; S Gregory; T Hubbard; S Humphray; A Hunt; M Jones; C Lloyd; A McMurray; L Matthews; S Mercer; S Milne; J C Mullikin; A Mungall; R Plumb; M Ross; R Shownkeen; S Sims; R H Waterston; R K Wilson; L W Hillier; J D McPherson; M A Marra; E R Mardis; L A Fulton; A T Chinwalla; K H Pepin; W R Gish; S L Chissoe; M C Wendl; K D Delehaunty; T L Miner; A Delehaunty; J B Kramer; L L Cook; R S Fulton; D L Johnson; P J Minx; S W Clifton; T Hawkins; E Branscomb; P Predki; P Richardson; S Wenning; T Slezak; N Doggett; J F Cheng; A Olsen; S Lucas; C Elkin; E Uberbacher; M Frazier; R A Gibbs; D M Muzny; S E Scherer; J B Bouck; E J Sodergren; K C Worley; C M Rives; J H Gorrell; M L Metzker; S L Naylor; R S Kucherlapati; D L Nelson; G M Weinstock; Y Sakaki; A Fujiyama; M Hattori; T Yada; A Toyoda; T Itoh; C Kawagoe; H Watanabe; Y Totoki; T Taylor; J Weissenbach; R Heilig; W Saurin; F Artiguenave; P Brottier; T Bruls; E Pelletier; C Robert; P Wincker; D R Smith; L Doucette-Stamm; M Rubenfield; K Weinstock; H M Lee; J Dubois; A Rosenthal; M Platzer; G Nyakatura; S Taudien; A Rump; H Yang; J Yu; J Wang; G Huang; J Gu; L Hood; L Rowen; A Madan; S Qin; R W Davis; N A Federspiel; A P Abola; M J Proctor; R M Myers; J Schmutz; M Dickson; J Grimwood; D R Cox; M V Olson; R Kaul; C Raymond; N Shimizu; K Kawasaki; S Minoshima; G A Evans; M Athanasiou; R Schultz; B A Roe; F Chen; H Pan; J Ramser; H Lehrach; R Reinhardt; W R McCombie; M de la Bastide; N Dedhia; H Blöcker; K Hornischer; G Nordsiek; R Agarwala; L Aravind; J A Bailey; A Bateman; S Batzoglou; E Birney; P Bork; D G Brown; C B Burge; L Cerutti; H C Chen; D Church; M Clamp; R R Copley; T Doerks; S R Eddy; E E Eichler; T S Furey; J Galagan; J G Gilbert; C Harmon; Y Hayashizaki; D Haussler; H Hermjakob; K Hokamp; W Jang; L S Johnson; T A Jones; S Kasif; A Kaspryzk; S Kennedy; W J Kent; P Kitts; E V Koonin; I Korf; D Kulp; D Lancet; T M Lowe; A McLysaght; T Mikkelsen; J V Moran; N Mulder; V J Pollara; C P Ponting; G Schuler; J Schultz; G Slater; A F Smit; E Stupka; J Szustakowki; D Thierry-Mieg; J Thierry-Mieg; L Wagner; J Wallis; R Wheeler; A Williams; Y I Wolf; K H Wolfe; S P Yang; R F Yeh; F Collins; M S Guyer; J Peterson; A Felsenfeld; K A Wetterstrand; A Patrinos; M J Morgan; P de Jong; J J Catanese; K Osoegawa; H Shizuya; S Choi; Y J Chen; J Szustakowki
Journal:  Nature       Date:  2001-02-15       Impact factor: 49.962

3.  Immunity and retroviral superantigens in humans.

Authors:  David L Woodland
Journal:  Trends Immunol       Date:  2002-02       Impact factor: 16.687

4.  Precursor RNAs harboring nonsense codons accumulate near the site of transcription.

Authors:  O Mühlemann; C S Mock-Casagrande; J Wang; S Li; N Custódio; M Carmo-Fonseca; M F Wilkinson; M J Moore
Journal:  Mol Cell       Date:  2001-07       Impact factor: 17.970

5.  Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses.

Authors:  R Kaul; S L Rowland-Jones; J Kimani; T Dong; H B Yang; P Kiama; T Rostron; E Njagi; J J Bwayo; K S MacDonald; A J McMichael; F A Plummer
Journal:  J Clin Invest       Date:  2001-02       Impact factor: 14.808

6.  Further analysis of the detailed structure of type B and C particles.

Authors:  A J Dalton
Journal:  J Natl Cancer Inst       Date:  1972-04       Impact factor: 13.506

7.  A stop codon in xeroderma pigmentosum group C families in Turkey and Italy: molecular genetic evidence for a common ancestor.

Authors:  E M Gozukara; S G Khan; A Metin; S Emmert; D B Busch; T Shahlavi; D M Coleman; M Miller; N Chinsomboon; M Stefanini; K H Kraemer
Journal:  J Invest Dermatol       Date:  2001-08       Impact factor: 8.551

8.  Identification and characterization of novel human endogenous retrovirus families by phylogenetic screening of the human genome mapping project database.

Authors:  M Tristem
Journal:  J Virol       Date:  2000-04       Impact factor: 5.103

9.  Epstein-Barr virus transactivates the human endogenous retrovirus HERV-K18 that encodes a superantigen.

Authors:  N Sutkowski; B Conrad; D A Thorley-Lawson; B T Huber
Journal:  Immunity       Date:  2001-10       Impact factor: 31.745

10.  Identification and cloning of endogenous retroviral sequences present in human DNA.

Authors:  M A Martin; T Bryan; S Rasheed; A S Khan
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

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  59 in total

Review 1.  Demystified...recombinant antibodies.

Authors:  K A Smith; P N Nelson; P Warren; S J Astley; P G Murray; J Greenman
Journal:  J Clin Pathol       Date:  2004-09       Impact factor: 3.411

2.  Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses.

Authors:  Katherine B Chiappinelli; Pamela L Strissel; Alexis Desrichard; Huili Li; Christine Henke; Benjamin Akman; Alexander Hein; Neal S Rote; Leslie M Cope; Alexandra Snyder; Vladimir Makarov; Sadna Budhu; Sadna Buhu; Dennis J Slamon; Jedd D Wolchok; Drew M Pardoll; Matthias W Beckmann; Cynthia A Zahnow; Taha Merghoub; Taha Mergoub; Timothy A Chan; Stephen B Baylin; Reiner Strick
Journal:  Cell       Date:  2015-08-27       Impact factor: 41.582

3.  Expression of human endogenous retrovirus type K (HML-2) is activated by the Tat protein of HIV-1.

Authors:  Marta J Gonzalez-Hernandez; Michael D Swanson; Rafael Contreras-Galindo; Sarah Cookinham; Steven R King; Richard J Noel; Mark H Kaplan; David M Markovitz
Journal:  J Virol       Date:  2012-05-16       Impact factor: 5.103

4.  Murine endogenous retroviruses and their transcriptional potentials.

Authors:  Jerry Boonyaratanakornkit; Alex Chew; Dewey D Y Ryu; David G Greenhalgh; Kiho Cho
Journal:  Mamm Genome       Date:  2004-11       Impact factor: 2.957

Review 5.  An alternative approach to medical genetics based on modern evolutionary biology. Part 4: HERVs in cancer.

Authors:  Frank P Ryan
Journal:  J R Soc Med       Date:  2009-11       Impact factor: 5.344

6.  A role for human endogenous retrovirus-K (HML-2) in rheumatoid arthritis: investigating mechanisms of pathogenesis.

Authors:  G Freimanis; P Hooley; H Davari Ejtehadi; H A Ali; A Veitch; P B Rylance; A Alawi; J Axford; A Nevill; P G Murray; P N Nelson
Journal:  Clin Exp Immunol       Date:  2010-03-16       Impact factor: 4.330

Review 7.  "Reverse genomics" and human endogenous retroviruses.

Authors:  David M Markovitz
Journal:  Trans Am Clin Climatol Assoc       Date:  2014

8.  Characterization of human endogenous retroviral elements in the blood of HIV-1-infected individuals.

Authors:  Rafael Contreras-Galindo; Mark H Kaplan; Angie C Contreras-Galindo; Marta J Gonzalez-Hernandez; Ilaria Ferlenghi; Fabiola Giusti; Eric Lorenzo; Scott D Gitlin; Michael H Dosik; Yasuhiro Yamamura; David M Markovitz
Journal:  J Virol       Date:  2011-10-26       Impact factor: 5.103

Review 9.  Human endogenous retroviruses and cancer: causality and therapeutic possibilities.

Authors:  Christina S Mullins; Michael Linnebacher
Journal:  World J Gastroenterol       Date:  2012-11-14       Impact factor: 5.742

Review 10.  Retrotransposon-derived elements in the mammalian genome: a potential source of disease.

Authors:  R Druker; E Whitelaw
Journal:  J Inherit Metab Dis       Date:  2004       Impact factor: 4.982

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