| Literature DB >> 12560049 |
M L Qi1, P Wang, L J Wang, R N Fu.
Abstract
A simple and accurate HPLC method for determination of oxcarbazepine (OXC) in a new tablet formulation is described. Chromatographic separation was achieved on a Diamonsil C18 column using a mobile phase consisting of acetonitrile, potassium phosphate monobasic buffer (pH 6.8) and water (36:8:56, v/v) at a flow rate of 1.0 ml/min. Absorbance was monitored at 255 nm where OXC has maximum absorption. The linear range of detection for OXC was from 9.96 to 99.6 microg/ml. The proposed method was validated for selectivity, precision, accuracy and limits of detection and quantitation, etc.Entities:
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Year: 2003 PMID： 12560049 DOI： 10.1016/s0731-7085(02)00602-7
Source DB: PubMed Journal: J Pharm Biomed Anal ISSN： 0731-7085 Impact factor: 3.935