Literature DB >> 12559169

Take care of your chromosomes lest cancer take care of you.

Richard S Maser1, Ronald A DePinho.   

Abstract

The analysis of compound mouse mutants for nonhomologous end-joining DNA double-strand break repair and those deficient for the p53 checkpoint pathway has provided a fascinating look at the carcinogenic consequences of the failure to properly repair DNA damage and to elicit appropriate checkpoints.

Entities:  

Mesh：

Year:  2003        PMID： 12559169     DOI： 10.1016/s1535-6108(02)00243-x

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  7 in total

1.  Degradation of p53, not telomerase activation, by E6 is required for bypass of crisis and immortalization by human papillomavirus type 16 E6/E7.

Authors:  H R McMurray; D J McCance
Journal:  J Virol       Date:  2004-06       Impact factor: 5.103

2.  The effect of gap length on double-strand break repair in Drosophila.

Authors:  Dena M Johnson-Schlitz; William R Engels
Journal:  Genetics       Date:  2006-05-15       Impact factor: 4.562

3.  Suppression of leukemia development caused by PTEN loss.

Authors:  Wei Guo; Suzanne Schubbert; James Y Chen; Bahram Valamehr; Sherly Mosessian; Hubing Shi; Nhi H Dang; Consuelo Garcia; Mariana F Theodoro; Marileila Varella-Garcia; Hong Wu
Journal:  Proc Natl Acad Sci U S A       Date:  2011-01-06       Impact factor: 11.205

4.  Impaired DNA damage checkpoint response in MIF-deficient mice.

Authors:  Alice Nemajerova; Patricio Mena; Gunter Fingerle-Rowson; Ute M Moll; Oleksi Petrenko
Journal:  EMBO J       Date:  2007-02-08       Impact factor: 11.598

Review 5.  Whole chromosome instability and cancer: a complex relationship.

Authors:  Robin M Ricke; Janine H van Ree; Jan M van Deursen
Journal:  Trends Genet       Date:  2008-07-31       Impact factor: 11.639

6.  Complex oncogenic translocations with gene amplification are initiated by specific DNA breaks in lymphocytes.

Authors:  Sarah M Wright; Yong H Woo; Travis L Alley; Bobbi-Jo Shirley; Ellen C Akeson; Kathy J Snow; Sarah A Maas; Rachel L Elwell; Oded Foreman; Kevin D Mills
Journal:  Cancer Res       Date:  2009-05-12       Impact factor: 12.701

7.  Bloom syndrome cells undergo p53-dependent apoptosis and delayed assembly of BRCA1 and NBS1 repair complexes at stalled replication forks.

Authors:  Albert R Davalos; Judith Campisi
Journal:  J Cell Biol       Date:  2003-09-29       Impact factor: 10.539
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.