I Kocijancic1, K Vidmar, M Zwitter, M Snoj. 1. Department of Radiology, Institute of Oncology, Zaloska 2, SI-1105 Ljubljana, Slovenia. ikocijancic@onko-i.si
Abstract
AIM: The aim of our study was to correlate spread of the lung cancer into the adrenal glands with the progression of the primary disease. METHODS: We diagnosed and confirmed adrenal metastases in 50 patients with non-small cell lung cancer (NSCLC). We correlated the site of the primary lung carcinoma with the site of the adrenal metastasis, and the adrenal metastasis pattern, ipsi-, contra-, and bilateral adrenal metastases, with the operability and number of other sites of metastatic disease. RESULTS: Adrenal metastases were ipsilateral in 20 patients, contralateral in 15 patients and bilateral in 15 patients. An inverse incidence of contra- and bilateral metastasis was observed in 37% of operated patients, and in 71% of patients with inoperable carcinoma. The difference between both groups was statistically significant (P=0.034). CONCLUSIONS: We suggest that an isolated ipsilateral adrenal metastasis in a patient with resectable primary NSCLC could be considered (and treated) as a localized disease rather than a symptom of systemic spread.
AIM: The aim of our study was to correlate spread of the lung cancer into the adrenal glands with the progression of the primary disease. METHODS: We diagnosed and confirmed adrenal metastases in 50 patients with non-small cell lung cancer (NSCLC). We correlated the site of the primary lung carcinoma with the site of the adrenal metastasis, and the adrenal metastasis pattern, ipsi-, contra-, and bilateral adrenal metastases, with the operability and number of other sites of metastatic disease. RESULTS:Adrenal metastases were ipsilateral in 20 patients, contralateral in 15 patients and bilateral in 15 patients. An inverse incidence of contra- and bilateral metastasis was observed in 37% of operated patients, and in 71% of patients with inoperable carcinoma. The difference between both groups was statistically significant (P=0.034). CONCLUSIONS: We suggest that an isolated ipsilateral adrenal metastasis in a patient with resectable primary NSCLC could be considered (and treated) as a localized disease rather than a symptom of systemic spread.
Authors: A Ra Cho; Ilhan Lim; Im Il Na; Du Hwan Choe; Joon Yeun Park; Byung Il Kim; Gi Jeong Cheon; Chang Woon Choi; Sang Moo Lim Journal: Nucl Med Mol Imaging Date: 2010-11-11
Authors: Madelon J H Metman; Charlotte L Viëtor; Auke J Seinen; Annika M A Berends; Patrick H J Hemmer; Michiel N Kerstens; Richard A Feelders; Gaston J H Franssen; Tessa M van Ginhoven; Schelto Kruijff Journal: Cancers (Basel) Date: 2021-12-29 Impact factor: 6.639