Literature DB >> 12558721

Physicians vary in approaches to the clinical management of delirium.

Molly Carnes1, Timothy Howell, Marjorie Rosenberg, Joseph Francis, Christopher Hildebrand, Jeffrey Knuppel.   

Abstract

OBJECTIVES: To ascertain the variation in strategies for managing delirium of physicians with expertise in geriatrics.
DESIGN: Cross-sectional mail survey.
SETTING: United States. PARTICIPANTS: A probability sample of physician members of the American Geriatrics Society. MEASUREMENTS: Management choices presented in a two-part case vignette of an older woman hospitalized with a hip fracture who develops mild and then severe delirium.
RESULTS: One hundred twenty-two respondents (43%) selected the three answers constituting current "best practice," 50 (18%) selected an unnecessary diagnostic test (brain imaging, lumbar puncture, or electroencephalogram), and 47 (17%) selected unnecessary pharmacologic therapy for mild delirium. For severe delirium, 270 (96%) selected pharmacological therapy, of whom 180 chose haloperidol alone, 55 chose lorazepam alone, 23 chose lorazepam in combination with haloperidol, and 12 wrote in another drug. Thirty percent of the respondents made any selection of lorazepam, alone or in combination with haloperidol, for mild or severe delirium. Sixty-one percent of those selecting haloperidol for severe delirium chose a dose greater than that recommended for geriatric patients. Sex, date of graduation from medical school, clinical specialty, completion of a geriatric fellowship, or certification in geriatrics had no significant effect on responses.
CONCLUSIONS: The common selection of lorazepam to treat delirium is troubling because benzodiazepines themselves are implicated in delirium. Selection of an initial dose of haloperidol higher than that recommended for geriatric patients by more than half of the respondents is also of concern. There is a paucity of sound clinical evidence to guide the choice of pharmacological agents for treating delirium in older hospitalized patients.

Entities:  

Mesh:

Year:  2003        PMID: 12558721     DOI: 10.1046/j.1532-5415.2003.51063.x

Source DB:  PubMed          Journal:  J Am Geriatr Soc        ISSN: 0002-8614            Impact factor:   5.562


  11 in total

1.  Mental Status Documentation: Information Quality and Data Processes.

Authors:  Charlene Weir; Bryan Gibson; Teresa Taft; Stacey Slager; Lacey Lewis; Nancy Staggers
Journal:  AMIA Annu Symp Proc       Date:  2017-02-10

Review 2.  Delirium: where do we stand?

Authors:  Chi-Un Pae; David M Marks; Changsu Han; Ashwin A Patkar; Prakash Masand
Journal:  Curr Psychiatry Rep       Date:  2008-06       Impact factor: 5.285

3.  Haloperidol overdosing in the treatment of agitated hospitalized older people with delirium: a retrospective chart review from a community teaching hospital.

Authors:  William Zirker; Igor Dorokhine; Clifford M Knapp; Nayan Patel; Mary Musuku
Journal:  Drugs Aging       Date:  2013-08       Impact factor: 3.923

4.  Barriers to translating emerging genetic research on smoking into clinical practice. Perspectives of primary care physicians.

Authors:  Alexandra E Shields; David Blumenthal; Kevin B Weiss; Catherine B Comstock; Douglas Currivan; Caryn Lerman
Journal:  J Gen Intern Med       Date:  2005-02       Impact factor: 5.128

5.  Delirium: underrecognized and undertreated.

Authors:  Chi-Un Pae; David M Marks; Changsu Han; Ashwin A Patkar; Prakash Masand
Journal:  Curr Treat Options Neurol       Date:  2008-09       Impact factor: 3.598

Review 6.  Assessment and Management of Delirium in Older Adults in the Emergency Department: Literature Review to Inform Development of a Novel Clinical Protocol.

Authors:  Tony Rosen; Scott Connors; Sunday Clark; Alexis Halpern; Michael E Stern; Jennifer DeWald; Mark S Lachs; Neal Flomenbaum
Journal:  Adv Emerg Nurs J       Date:  2015 Jul-Sep

7.  Recognition and labeling of delirium symptoms by intensivists: does it matter?

Authors:  Catherine Z Cheung; Shabbir M H Alibhai; Michael Robinson; George Tomlinson; Dean Chittock; John Drover; Yoanna Skrobik
Journal:  Intensive Care Med       Date:  2007-12-18       Impact factor: 17.440

8.  Study protocol for the recreational stimulation for elders as a vehicle to resolve delirium superimposed on dementia (Reserve For DSD) trial.

Authors:  Ann M Kolanowski; Donna M Fick; Mark S Litaker; Linda Clare; Doug Leslie; Malaz Boustani
Journal:  Trials       Date:  2011-05-11       Impact factor: 2.279

Review 9.  Antipsychotics for treatment of delirium in hospitalised non-ICU patients.

Authors:  Lisa Burry; Sangeeta Mehta; Marc M Perreault; Jay S Luxenberg; Najma Siddiqi; Brian Hutton; Dean A Fergusson; Chaim Bell; Louise Rose
Journal:  Cochrane Database Syst Rev       Date:  2018-06-18

10.  The use of clonidine in elderly patients with delirium; pharmacokinetics and hemodynamic responses.

Authors:  Karen Roksund Hov; Bjørn Erik Neerland; Anders Mikal Andersen; Øystein Undseth; Vegard Bruun Wyller; Alasdair M J MacLullich; Eva Skovlund; Eirik Qvigstad; Torgeir Bruun Wyller
Journal:  BMC Pharmacol Toxicol       Date:  2018-06-08       Impact factor: 2.483

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.