Literature DB >> 12558412

Rapid and amenable suzuki coupling reaction in water using microwave and conventional heating.

Nicholas E Leadbeater1, Maria Marco.   

Abstract

It is possible to prepare biaryls in good yield very rapidy (5-10 min) on small (1 mmol) and larger (10-20 mmol) scales from aryl halides and phenylboronic acid using water as a solvent and palladium acetate as catalyst. The reaction can be performed equally well using microwave and conventional heating, showing that using these conditions probably no nonthermal microwave effects are associated with the impressive speed of the reaction.

Entities:  

Year:  2003        PMID: 12558412     DOI: 10.1021/jo0264022

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  6 in total

1.  Combining the use of solid-supported transition metal catalysis with microwave irradiation in solution-phase parallel library synthesis.

Authors:  Michael G Organ; Stanislas Mayer; Franck Lepifre; Blaise N'Zemba; Jayantilal Khatri
Journal:  Mol Divers       Date:  2003       Impact factor: 2.943

2.  Cross coupling: When is free really free?

Authors:  Nicholas E Leadbeater
Journal:  Nat Chem       Date:  2010-11-07       Impact factor: 24.427

3.  Computationally Assisted Mechanistic Investigation and Development of Pd-Catalyzed Asymmetric Suzuki-Miyaura and Negishi Cross-Coupling Reactions for Tetra-ortho-Substituted Biaryl Synthesis.

Authors:  Nitinchandra Dahyabhai Patel; Joshua D Sieber; Sergei Tcyrulnikov; Bryan J Simmons; Daniel Rivalti; Krishnaja Duvvuri; Yongda Zhang; Donghong A Gao; Keith R Fandrick; Nizar Haddad; Kendricks So Lao; Hari Prasad Reddy Mangunuru; Soumik Biswas; Bo Qu; Nelu Grinberg; Scott Pennino; Heewon Lee; Jinhua J Song; B Frank Gupton; Neil K Garg; Marisa C Kozlowski; Chris H Senanayake
Journal:  ACS Catal       Date:  2018-09-20       Impact factor: 13.084

4.  Arylboronic acids as versatile coupling partners in fast microwave promoted oxidative Heck chemistry.

Authors:  Murugaiah M S Andappan; Peter Nilsson; Mats Larhed
Journal:  Mol Divers       Date:  2003       Impact factor: 2.943

5.  "On-water" catalyst-free ecofriendly synthesis of the hantzsch dihydropyridines.

Authors:  Amit Pramanik; Manabendra Saha; Sanjay Bhar
Journal:  ISRN Org Chem       Date:  2012-08-12

6.  SAR:s for the Antiparasitic Plant Metabolite Pulchrol. 1. The Benzyl Alcohol Functionality.

Authors:  Paola Terrazas; Efrain Salamanca; Marcelo Dávila; Sophie Manner; Alberto Giménez; And Olov Sterner
Journal:  Molecules       Date:  2020-07-04       Impact factor: 4.411

  6 in total

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