Literature DB >> 12557539

[The effect of HJ-1 NO--HFJV respirator on treating pulmonary edema caused by seawater drowning].

Yanrong Fan1, Wendu Dong, Jingjin He, Li Du, Genxing Xu, Xinjuan Liu, Yun Pei, Gengfeng Fu, Guohua Ma.   

Abstract

The study was to observe the therapeutic effect of HJ-1 NO--HFJV respirator on treating pulmonary edema caused by seawater drowning. Seawater was infused into the rabbit's lung to establish the animal model of pulmonary edema caused by seawater drowning(PE-SWD). Then the animals were divided into three groups: simple PE-SWD model as control group, treat group(animal model treated with HFJV respirator and four medicines) and HFJV respiratior plus NO group. Pao2, Sao2 and pH were measured by the blood-gas analyzer. The survival time and seawater drowing-respiratiory distress syndrom(SW-RDS) were observed. The results showed that Pao2, Sao2 in NO group were remarkably higher than that of PE-SWD control group, and the survival time was longer than that of medicine treated group and the incidence of SW-RDS decreased to zero. We assume that HJ-1 NO-HFJV respirator is efficient on treating pulmonary edema.

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Year:  2002        PMID: 12557539

Source DB:  PubMed          Journal:  Sheng Wu Yi Xue Gong Cheng Xue Za Zhi        ISSN: 1001-5515


  1 in total

1.  4-hydroxyphenylacetic acid attenuated inflammation and edema via suppressing HIF-1α in seawater aspiration-induced lung injury in rats.

Authors:  Zhongyang Liu; Ronggang Xi; Zhiran Zhang; Wangping Li; Yan Liu; Faguang Jin; Xiaobo Wang
Journal:  Int J Mol Sci       Date:  2014-07-21       Impact factor: 5.923

  1 in total

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