Literature DB >> 125565

Allosteric activation and competitive inhibition of yeast phosphofructokinase by d-fructose.

A Betz, U Röttger, K H Kreuzberg.   

Abstract

Purified phosphofructokinase from bakers yeast is activated by D-fructose in low concentrations (up to 1 mM) and inhibited by high concentrations. The stimulatory effect of D-fructose is similar, but smaller than that of AMP. In the presence of AMP (0.4 mM or higher) D-fructose does no longer stimulate, but its inhibitory effect persists (KI = 8 mM). Its dualistic action on phosphofructokinase activity indicates that D-fructose might induce low frequency in glycolytic oscillations by direct interaction with the enzyme.

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Year:  1975        PMID： 125565     DOI： 10.1007/bf00436338

Source DB:  PubMed          Journal:  Arch Microbiol        ISSN： 0302-8933            Impact factor:   2.552


  7 in total

1.  Phosphofructokinase and the Pasteur effect.

Authors:  J V PASSONNEAU; O H LOWRY
Journal:  Biochem Biophys Res Commun       Date:  1962-02-20       Impact factor: 3.575

2.  Membrane transport as controlling pacemaker of glycolysis in Saccharomyces carlsbergensis.

Authors:  J U Becker; A Betz
Journal:  Biochim Biophys Acta       Date:  1972-08-09

3.  Oscillations of glycolytic intermediates in yeast cells.

Authors:  A Ghosh; B Chance
Journal:  Biochem Biophys Res Commun       Date:  1964-06-01       Impact factor: 3.575

4.  A new jpurification procedure for yeast phosphofructokinase minimizing proteolytic degradation.

Authors:  W Diezal; H J Böhme; K Nissler; R Freyer; W Heilmann; G Kopperschläger; E Hofmann
Journal:  Eur J Biochem       Date:  1973-10-18

5.  [Preparative demonstration of homogenous phosphofructokinase from yeast].

Authors:  K Nissler; S Friedrich; E Hofmann
Journal:  Acta Biol Med Ger       Date:  1972

6.  [Purification and properties of phosphofructokinase from yeast].

Authors:  R Jauch; C Riepertinger; F Lynen
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1970-01

7.  [Yeast phosphofructokinase. Kinetic relations between substrate and effector-binding sites].

Authors:  R Freyer; M Kubel; E Hofmann
Journal:  Eur J Biochem       Date:  1970-12
  7 in total
  1 in total

1.  Carbon accumulation in Rhodotorula glutinis induced by nitrogen limitation.

Authors:  Julien Cescut; Luc Fillaudeau; Carole Molina-Jouve; Jean-Louis Uribelarrea
Journal:  Biotechnol Biofuels       Date:  2014-12-09       Impact factor: 6.040
  1 in total

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