| Literature DB >> 12552459 |
Hernan Valdez1, Ronald Mitsuyasu, Alan Landay, Anne D Sevin, Ellen S Chan, John Spritzler, Spyros A Kalams, Richard B Pollard, John Fahey, Lawrence Fox, Ann Namkung, Scharla Estep, Ronald Moss, David Sahner, Michael M Lederman.
Abstract
To ascertain whether CD4(+) lymphocyte increases induced by interleukin (IL)-2 enhanced in vivo immune responses, 38 human immunodeficiency virus (HIV)-infected patients who had received highly active antiretroviral therapy (HAART) or HAART and IL-2 for at least 60 weeks were immunized with tetanus toxoid, inactivated glycoprotein 120-depleted HIV-1, and hepatitis A and B vaccines. Despite dramatic increases in CD4(+) lymphocyte counts, IL-2 did not enhance immunization responses.Entities:
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Year: 2003 PMID： 12552459 DOI： 10.1086/346056
Source DB: PubMed Journal: J Infect Dis ISSN： 0022-1899 Impact factor: 5.226