| Literature DB >> 12552450 |
Richard A Oberhelman1, Robert H Gilman, Patricia Sheen, Julianna Cordova, David N Taylor, Mirko Zimic, Rina Meza, Juan Perez, Carlos LeBron, Lilia Cabrera, Frank G Rodgers, David L Woodward, Lawrence J Price.
Abstract
Campylobacter jejuni is a major cause of pediatric diarrhea in developing countries-free-ranging chickens are presumed to be a common source. Campylobacter strains from monthly surveillance and diarrhea cases were compared by means of restriction-fragment length polymorphism (RFLP), rapid amplified polymorphic DNA, and Lior serotyping. RFLP analysis of 156 human and 682 avian strains demonstrated identical strains in chickens and humans in 29 (70.7%) of 41 families, and 35%-39% of human isolates from diarrhea and nondiarrhea cases were identical to a household chicken isolate. Isolation of the same RFLP type from a household chicken and a human within 1 month was highly protective against diarrhea (odds ratio, 0.07; P<.005). Campylobacter strains from symptomatic humans were unlikely to be identical to strains recently carried by household chickens, limiting the potential benefits from household-based control measures.Entities:
Mesh：
Year: 2003 PMID： 12552450 DOI： 10.1086/367676
Source DB: PubMed Journal: J Infect Dis ISSN： 0022-1899 Impact factor: 5.226