Literature DB >> 12551707

Handling of computational in vitro/in vivo correlation problems by Microsoft Excel II. Distribution functions and moments.

Frieder Langenbucher1.   

Abstract

MS Excel is a useful tool to handle in vitro/in vivo correlation (IVIVC) distribution functions, with emphasis on the Weibull and the biexponential distribution, which are most useful for the presentation of cumulative profiles, e.g. release in vitro or urinary excretion in vivo, and differential profiles such as the plasma response in vivo. The discussion includes moments (AUC and mean) as summarizing statistics, and data-fitting algorithms for parameter estimation.

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Year:  2003        PMID： 12551707     DOI： 10.1016/s0939-6411(02)00115-7

Source DB:  PubMed          Journal:  Eur J Pharm Biopharm        ISSN： 0939-6411            Impact factor:   5.571


  4 in total

1.  Improving of the accuracy of in vitro-in vivo linear correlation using kinetic models for ultra sustained release theophylline tablets.

Authors:  E Karasulu; S Aktogu; H Y Karasulu; A Aydogdu; I Tuglular; G Ertan
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2003 Oct-Dec       Impact factor: 2.441

2.  In vivo bioequivalence and in vitro similarity factor (f2) for dissolution profile comparisons of extended release formulations: how and when do they match?

Authors:  John Z Duan; Kareen Riviere; Patrick Marroum
Journal:  Pharm Res       Date:  2011-02-02       Impact factor: 4.200

Review 3.  In vitro-in vivo correlation: perspectives on model development.

Authors:  Ying Lu; Sungwon Kim; Kinam Park
Journal:  Int J Pharm       Date:  2011-01-13       Impact factor: 5.875

4.  Development of a New Type of Prolonged Release Hydrocodone Formulation Based on Egalet® ADPREM Technology Using In Vivo-In Vitro Correlation.

Authors:  Pernille H Hemmingsen; Anne-Mette Haahr; Christine Gunnergaard; Jean-Michel Cardot
Journal:  Pharmaceutics       Date:  2011-03-09       Impact factor: 6.321
  4 in total

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