Literature DB >> 12550806

Defining the Neutral Zone of sheep intervertebral joints during dynamic motions: an in vitro study.

Rosemary E Thompson1, Timothy M Barker, Mark J Pearcy.   

Abstract

OBJECTIVE: To make an experimental assessment of the Neutral Zone of intervertebral joints during dynamic spinal motion in flexion/extension, lateral bending and axial rotation and to develop a criterion for its definition.
DESIGN: Dynamic mechanical testing of sheep intervertebral joints with a six-degree of freedom robotic facility under position control.
BACKGROUND: The Neutral Zone is defined as a region of no or little resistance to motion in the middle of an intervertebral joint's range of movement. Previous studies have used quasi-static loading regimes that do not model physiological activity. This study simulated physiological movements using a robotic testing facility to address this issue.
METHODS: Five spines from mature sheep were used and three motion segments were tested from each spine. The robotic facility enabled the testing regime to be defined for each individual joint based on its geometry. The joints were tested by cycling through the full range of physiological movement in flexion/extension, lateral bending and axial rotation.
RESULTS: A Neutral Zone was found to exist during dynamic movements only in flexion/extension. The results suggested that a Neutral Zone does not exist in lateral bending or axial rotation. The zygapophysial joints were shown to be significant in determining the mechanics of the intervertebral joints as their removal increased the Neutral Zone in all cases. A new criterion for defining the size of the Neutral Zone during dynamic motion was proposed and its implications for spinal movements in life discussed.
CONCLUSIONS: A Neutral Zone exists in flexion/extension during dynamic movements of intervertebral joints and is a feature of the natural range of joint motion. This has important implications for the muscular control of the spine consisting of several intrinsically lax joints stacked on one another. RELEVANCE: The existence of a Neutral Zone is a feature of the natural range of joint motion and requires complex control of intervertebral joints by the spinal muscles. Defining the biomechanical response throughout the physiological range of motion (RoM) is important in understanding possible injury and rehabilitation mechanisms.

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Year:  2003        PMID: 12550806     DOI: 10.1016/s0268-0033(02)00180-8

Source DB:  PubMed          Journal:  Clin Biomech (Bristol, Avon)        ISSN: 0268-0033            Impact factor:   2.063


  13 in total

1.  Biomechanical Comparison of Robotically Applied Pure Moment, Ideal Follower Load, and Novel Trunk Weight Loading Protocols on L4-L5 Cadaveric Segments during Flexion-Extension.

Authors:  Charles R Bennett; Denis J DiAngelo; Brian P Kelly
Journal:  Int J Spine Surg       Date:  2015-07-17

2.  Vertebral position alters paraspinal muscle spindle responsiveness in the feline spine: effect of positioning duration.

Authors:  Weiqing Ge; Cynthia R Long; Joel G Pickar
Journal:  J Physiol       Date:  2005-10-06       Impact factor: 5.182

3.  New methodology for multi-dimensional spinal joint testing with a parallel robot.

Authors:  Matthew R Walker; James P Dickey
Journal:  Med Biol Eng Comput       Date:  2007-01-19       Impact factor: 2.602

4.  The effect of loading rate and degeneration on neutral region motion in human cadaveric lumbar motion segments.

Authors:  Ralph E Gay; Brice Ilharreborde; Kristin Zhao; Emir Boumediene; Kai-Nan An
Journal:  Clin Biomech (Bristol, Avon)       Date:  2007-09-21       Impact factor: 2.063

5.  Sheep cervical spine biomechanics: a finite element study.

Authors:  Nicole A DeVries Watson; Anup A Gandhi; Doug C Fredericks; Joseph D Smucker; Nicole M Grosland
Journal:  Iowa Orthop J       Date:  2014

6.  Does the neutral zone quantification method matter? Efficacy of evaluating neutral zone during destabilization and restabilization in human spine implant testing.

Authors:  T Di Pauli von Treuheim; L Zengerle; A C Hecht; J C Iatridis; H J Wilke
Journal:  J Biomech       Date:  2021-09-21       Impact factor: 2.712

7.  Kinematic and temporal interactions of the lumbar spine and hip during trunk extension in healthy male subjects.

Authors:  Stephan Milosavljevic; Poonam Pal; David Bain; Gillian Johnson
Journal:  Eur Spine J       Date:  2007-08-29       Impact factor: 3.134

8.  Effects of cement augmentation on the mechanical stability of multilevel spine after vertebral compression fracture.

Authors:  Eelin Tan; Tian Wang; Matthew H Pelletier; William R Walsh
Journal:  J Spine Surg       Date:  2016-06

9.  Load-relaxation properties of the human trunk in response to prolonged flexion: measuring and modeling the effect of flexion angle.

Authors:  Nima Toosizadeh; Maury A Nussbaum; Babak Bazrgari; Michael L Madigan
Journal:  PLoS One       Date:  2012-11-05       Impact factor: 3.240

10.  Quantifying intervertebral disc mechanics: a new definition of the neutral zone.

Authors:  Theodoor H Smit; Manon Slm van Tunen; Albert J van der Veen; Idsart Kingma; Jaap H van Dieën
Journal:  BMC Musculoskelet Disord       Date:  2011-02-07       Impact factor: 2.362

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